Model: 20-month-old male C57BL/6 mice 
Dosage: 3,000 to 4,000 µg of ouabain dissolved in 27,000 to 36,000 µL of PBS injected twice per week every third week over a period of three months

AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions

Harvard and MIT scientists analyze decades of publicly available molecular studies with a new AI platform to uncover hundreds of previously hidden anti-aging strategies, like the drug ouabain.

A new AI platform has uncovered hundreds of pro-longevity agents based on the reanalysis of millions of mouse and human gene expression samples.

Aging &amp; Longevity

How to Support Muscle Function with Age: Top Evidence-Based Supplements

Data suggest certain supplements, such as L-carnitine, vitamin D, and essential minerals, support muscle function and physical performance in adults of advanced age.

Researchers from University College London review data supporting that supplements, like vitamin D, L-carnitine, and essential minerals, support muscle function during aging.

Skin &amp; Muscle

The Rise of China’s Longevity Movement: A Quest to Defy Aging

China’s national project to crush aging encompasses longevity labs, “immortality islands,” and grapeseed pills, as well as exorbitant claims based on sometimes questionable science.

(Attendees at a conference in Shanghai try out a cryogenic chamber in which temperatures plummeted to approximately -200 degrees Fahrenheit, meant to slow aging | New York Times)

A surge in the Chinese public’s interest in longevity science has led to substantial investments from the state and private companies in aging research.

Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Immunity

The interventions that may help fix or reset circadian rhythms, which decline with age. 

A representation of Kairos, not to be confused with Kronos (original image: misel-trogir.com).

Search Result: supplements

AI Analyzes Millions of Molecular Profiles to Uncover Overlooked Aging Interventions

How to Support Muscle Function with Age: Top Evidence-Based Supplements

The Rise of China’s Longevity Movement: A Quest to Defy Aging

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Beyond Aligning Life with Light: Supplements that Counter Circadian Decline