Pioneering expert in NAD+ metabolism, Shin-Ichiro Imai, MD, PhD, explains the critical role of NAD+ in preventing chronic kidney disease, the ninth leading cause of death worldwide. 


Dr. Shin-Ichiro Imai (image: mspremium.com)

Model: Naturally aged C57BL/6J mice

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

A new study provides data suggesting compromised intestinal function with age and that fasting for short periods promotes intestinal regeneration and function in aged mice.

(A dysfunctional intestinal barrier that leaks harmful substances and bacteria into circulation develops with age | The Amino Company)

Alternate-day fasting, a form of intermittent fasting, reverses age-related intestinal barrier leakage in old mice.

Aging &amp; Longevity

Dr. Sinclair and collaborators show that an age-reversal technology that rejuvenates cells protects neurons from inflammation and cell death in mice. 

Brain &amp; Neurons

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Model: Male Wistar rats (4-month-old young rats and 24-month-old old rats)
Dosage: Oral administration of the trypsin inhibitor tranexamic acid in drinking water for 14 days at a minimum dose of 0.39 g/kg/day after consuming about 40 mL/day of water

Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within

University of California, San Diego researchers show digestive enzyme leakage from the intestines contributes to organ damage in old rats, offering what may be a new way to explain aging.

(Principal investigator, Geert Schmid-Schönbein | voiceofsandiego.org)

Search Result: intestine

Expert Explains Role of NAD+ in Preventing Age-Related Kidney Disease

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

Age-Reversal Tech Protects Against Neurodegeneration in Latest David Sinclair Study

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within