Participants: Healthy middle-aged to older adults (average age: ~53 years) 
Dosage: 1,000 mg/day of urolithin A for 28 days

Supplementing healthy adults with urolithin A —a compound produced by our gut bacteria— counters signs of age-related immune system decline.  

Principal investigator Dr. Florian R. Greten (image: hessen-schafft-wissen.de).

Immunity

The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

According to French scientists, no organ system appears as vulnerable to aging as the cardiovascular system, and anti-aging therapeutics may help mitigate the effects of cardiovascular disease.

(The principal investigator behind the review, aging researcher Guido Kroemer | Olympiad in Cardiovascular Medicine)

Anti-aging therapeutics may prevent and slow age-related cardiovascular dysfunction.

Cardiovascular

Chinese scientists have genetically engineered stem cells capable of rejuvenating the health, including the cognition, of aged macaques. 

A young crab-eating macaque (image: shutterstock.com). 

Aging &amp; Longevity

Model: Primary hippocampal neurons from non-transgenic C57BL/6 (nTg) and triple-transgenic 3xTg-AD mice; age groups: young (2–6 mo), middle (8–11 mo), and old (17–28 mo).
Dosage: Nicotinamide 2 mM + EGCG 2 µM applied to cultured neurons for 16 h (in vitro).

Study shows that brief nicotinamide + EGCG treatment restores neuronal energy in 16–24 hours, restores autophagy, reduces amyloid-beta buildup, and boosts neuron survival by ~22% in aging/Alzheimer’s lab models.

Brain &amp; Neurons

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

An aging research aficionado, Dr. Josh Helman, shares five supplements that can help fight the effects of aging: nitric oxide, NMN, honokiol, modified citrus pectin, and creatine.

(Harvard-trained aging expert, Dr. Josh Helman | Jupiter Medical Center)

Harvard-trained aging expert Dr. Josh Helman unveils his top five supplements to fight against aging.

Search Result: gene therapy

Urolithin Supplement Counters Immune System Aging, New Human Trial Shows

The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

Anti-Aging Breakthrough: Stem Cells Reverse Signs of Aging in Monkeys

Nicotinamide + EGCG Reboot Autophagy and Ease Hallmarks of Brain Aging

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements