<p>Model: 20-month-old female C57BL/J mice </p>
<p>Dosage: 10 nmol/kg/day of semaglutide </p>


Semaglutide extends mouse lifespan and targets signs of aging, such as diminished NAD+, while mimicking the anti-aging effects of caloric restriction (consuming fewer calories). 


The study was led by Dr. Danica Chen (image: berkeley.edu). 

Aging &amp; Longevity

<p>Model: Male C57BL/6J mice</p>
<p>Dosage: 150 mg/kg/day of diallyl sulforated compounds in food</p>


Diallyl sulfonated compounds (DAS), found in garlic, extend the lifespan of mice while counteracting signs of aging, such as grip weakness and memory loss. 

Dr. Vivian Capilla-González, one of the researchers on the study (image: cde.ual.es).

<p>Model: 24-month-old male C57BL/6J mice </p>
<p>Dosage: 1% w/v of betaine for three weeks </p>


The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Immunity

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<p data-start="97" data-end="197">Model: Aged mice (18 months old, C57BL/6 strain) and aged rhesus macaques (18–21 years old).</p>
<p data-start="97" data-end="197">Dosage: Mice received 100 µg of EVs^ABPC via tail vein injection twice per week for 4 weeks.<br data-start="297" data-end="300" data-is-only-node="" />Rhesus macaques received 200 µg/kg of EVs^ABPC intravenously once per week for 20 weeks.</p>
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Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Researchers discover that deer antler stem cells can restore bone density, slow aging, and reverse biological age in mice and primates.

The interventions that may help fix or reset circadian rhythms, which decline with age. 

A representation of Kairos, not to be confused with Kronos (original image: misel-trogir.com).

Search Result: coordination

Semaglutide (Ozempic) Enhances the Most Powerful Driver of Longevity & Boosts NAD+ in Mice, New Study Shows

Garlic Compound Extends Life, Builds Strength, and Boosts Memory, New Study Shows

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Beyond Aligning Life with Light: Supplements that Counter Circadian Decline