Engineered Brain “Wiring” Could One Day Help Treat Age-Related Memory Loss

Duke University scientists have successfully induced new neuronal connections in the brains of mice, leading to improvements in social interaction and stress resilience. 

The Principal Investigator of the study, Kafui Dzirasa, MD, PhD (image: medschool.duke.edu). 

Brain &amp; Neurons

Participants: Older adults (ages 60 to 80) with mild cognitive impairment 
Dosage: 320 mg/day of anthocyanin capsules for 24 weeks

Anthocyanin, a compound found in berries, reduces inflammation and heart disease markers in older adults at risk for dementia.  

Lead author of the study, Dr. Miguel Germán Borda (image: noticias.cun.es).

Cardiovascular

Advanced Alzheimer’s Can Be Reversed With NAD+ Restoration, Study Shows in Mice

Researchers at Case Western Reserve University have shown that late-stage neurodegeneration may be biologically reversible, at least in the right conditions, in mice.

(Case Western Reserve University | Cleveland 19)

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

A naturally occurring compound, α-lipoic acid, helped elderly mice think like younger mice by restoring energy balance and calming brain inflammation, according to Second Hospital of Hebei Medical University researchers.

(Alpha-lipoic acid’s molecular structure | Sasha’s of Saratoga)

Model: 14- to 15-month-old male C57BL/6J mice
Dosage: 50 mg injection of 3′-deoxyadenosine (cordycepin) because it was shown not to be absorbed if administered orally

Mushroom Compound Prolongs Lifespan If Taken At Correct Time

In mice, cordycepin—a molecule found in cordyceps mushrooms—prolongs lifespan and improves memory, strength, cardiac function, hormone levels, and metabolism. 


Cordyceps mushrooms (image: antioxi-supplements.com). 

Search Result: cognitive impairment

Can Engineered “Rewiring” One Day Help Treat Brain Aging? New Duke University Findings

Anthocyanin Supplement Shows Anti-Inflammatory and Heart Health Benefits in New Study

Advanced Alzheimer’s Can Be Reversed With NAD+ Restoration, Study Shows in Mice

Mitochondria-Made Molecule Reverses Memory Loss with Advanced Age

Cordyceps Mushroom Molecule Prolongs Lifespan If Taken At Correct Time of Day, New Study Shows