Model: C57BL/6 mice
Dosage: 500 mg/kg/day of SRN-901 via oral gavage for six days per week starting at 18 months of age; 14.4 ppm of rapamycin mixed in food starting at 18 months of age; 300 mg/kg/day of NMN via oral gavage for six days per week starting at 18 months of age; and 300 mg/kg/day of NR via oral gavage for six days per week starting at 18 months of age

Seragon Publishes Record-Breaking SRN-901 Longevity Data, Demonstrating 33% Lifespan Extension in Mice

In a newly published mouse study, SRN-901 extended remaining lifespan by 33%, slowed frailty progression, and lowered tumor incidence.

Seragon’s SRN-901 extended the remaining lifespan of adult mice by 33%, attenuated frailty progression by 70%, and reduced tumor incidence by 30.53%, according to a newly published preclinical study.

Aging &amp; Longevity

Chinese scientists have genetically engineered stem cells capable of rejuvenating the health, including the cognition, of aged macaques. 

A young crab-eating macaque (image: shutterstock.com). 

Model: C57BL6/J
Dosage: 300 mg/kg/day of NMN in drinking water

NMN Protects Against Intestinal Damage Induced by Cancer Radiotherapy

The NAD+ precursor nicotinamide mononucleotide (NMN) reduces intestinal injury induced by radiation exposure and largely restores gut bacteria diversity in mice. 


(Cross-section of the intestine | Joan Carles Juarez, shutterstock)

Wild-type mtKeima transgenic mice/ Wild-type C57BL/6J mice
Nicotinamide Riboside: Oral supplementation via drinking water (24 mM) for 10 months

NIA Successfully Halts Age-Related Hearing Loss with NR

National Institute of Aging (NIA) scientists show that NR, a precursor to the life-preserving nicotinamide adenine dinucleotide (NAD+), exerts protective effects against age-related hearing loss in mice.  


NAD+ Boosting Agent Suppresses Brain Tumor Growth

Mitchell Cancer Institute (MCI) researchers find that elevated NAD+ levels help prevent the growth of chemotherapy-resistant brain tumor cells. 

Senior author, Dr. Robert W. Sobol | University of Southern Alabama Health 

Search Result: Tumor Suppression

Seragon Publishes Record-Breaking SRN-901 Longevity Data, Demonstrating 33% Lifespan Extension in Mice

Anti-Aging Breakthrough: Stem Cells Reverse Signs of Aging in Monkeys

Study Shows NMN Protects Against Intestinal Damage Induced by Cancer Radiotherapy

NIA Researchers Show NR Halts Age-Related Hearing Loss

MCI Scientists Find NAD⁺ Boosting Agent Suppresses Brain Tumor Growth