University of California (UC) Berkeley scientists moderately extend the lifespan of old mice by giving them oxytocin and a compound that inhibits inflammation.  

Aging &amp; Longevity

Model: UM-HET3 Mice 
Dosage: 0, 75, 150, 300, 600, and 1200 ng epicatechin/mg food; 0, 0.075, 0.15, 0.3, 0.6, and 1.2 ng halofuginone/mg food; and 0, 37.5, 75, 150, 300, and 600 ng mitoglitazone/mg food, all given ad libitum in food starting at seven months old

Three Compounds Show Promise for Male Longevity

Data from a rigorous longevity study show promise for three new compounds, adding to the repertoire of mouse lifespan-extending substances.

(The three compounds’ effects on median lifespan extension | Rapamycin Longevity News)

The world’s most rigorous longevity study presents data showing promise for three new lifespan-extending compounds in male mice.

α-Lipoic Acid: Efficacy, Safety, and Dosage

α-lipoic acid is an antioxidant naturally produced by the body, which is also available as a supplement, and human trials indicate that it has neuroprotective and male fertility-enhancing effects.

(α-lipoic acid’s molecular structure | Neuroneeds)

α-lipoic acid is a potent antioxidant, which human trials suggest has neuroprotective and male fertility-enhancing properties.

Metabolism

Model: 39 adults between 18 and 30 years old and 36 adults between 65 and 80 years old
Dosage: ∼595 mg NO3− twice daily from two 70 mL shots of nitrate-rich beetroot juice

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

A new human trial yields data showing that nitrate-rich beetroot juice alters the oral microbe composition and lowers blood pressure in older participants.

A new human trial provides evidence that nitrate-rich beetroot juice beneficially modifies the oral microbe composition and lowers blood pressure in older individuals.

Cardiovascular

Does NAD+ (nicotinamide adenine dinucleotide) really help with aging? A team of international scientists reviews the latest and ongoing clinical trials.

Part of the research team, including Dr. Evandro Fei Fang (middle), from the University of Oslo and Akershus University Hospital in Norway (image: med.uio.no). 

Search Result: Supplement

New UC Berkeley Study: Oxytocin and Anti-Inflammatory Combo Prolongs Life

Three Compounds Show Promise for Male Longevity

An Overview of α-Lipoic Acid: Efficacy, Safety, and Dosage

Human Trial Finds Nitrate-Enhanced Juice Lowers Blood Pressure

NAD+ and Aging: What the Latest Research Says