Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity. 


Brain &amp; Neurons

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


Aging &amp; Longevity

An Ordinary Guy Tries Bryan Johnson’s Blueprint Longevity Routine

Podcaster Nick Tucker tries Bryan Johnson’s Blueprint longevity protocol for a month and reverses his biological age — a prediction of how long you have left.

(Hard Reset podcaster Nick Tucker [left] alongside longevity guru Bryan Johnson [right] | freethink.com)

Undergoing Bryan Johnson’s Blueprint protocol — an overhaul of supplementation, diet, and exercise — propelled age-reversing effects for the podcaster Nick Tucker.

David Sinclair’s 2024 Anti-Aging Supplement Protocol

Longevity expert Dr. David Sinclair's 2024 anti-aging protocol includes NMN, fish oil, lipoic acid, resveratrol, metformin, spermidine, and more.

Based on human evidence, Harvard and MIT scientists determine the most promising anti-aging interventions, including NAD+ precursors, spermidine, and senolytics. 


MIT’s Leonard Guarente, Ph.D. (image: amacad.org), Harvard’s David Sinclair, Ph.D. (image: buckinstitute.org), and University of Paris Descartes’ Guido Kromer, Ph.D., M.D. (image: createcures.org). 

David Sinclair and fellow top aging biology researchers review clinical trials pertaining to the eight anti-aging compounds. 

Search Result: Spermidine

Spermidine: A Promising Nutrient for Brain Health and Cognitive Aging

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol

An Ordinary Guy Tries Bryan Johnson’s Blueprint Longevity Routine

David Sinclair’s 2024 Anti-Aging Supplement Protocol

David Sinclair and Colleagues Summarize 8 Anti-Aging Medicines Applicable to Humans