Bryan Johnson’s “Clone”: Where the Sci-Fi Ends and the Science Begins

The biohacker says his “newborn” clone could supply young blood, test experimental treatments, and eventually grow replacement organs.

(Bryan Johnson says he’s cloned himself, which could supply young blood, help test experimental treatments, and eventually grow replacement organs. | Futurism)

Aging &amp; Longevity

Participants: Healthy males (age range: 70-76)
Dosage: 1 mg per day of rapamycin for 8 weeks

Supplementing with rapamycin leads to improvements in cardiac and vascular function in older men, suggesting this longevity-associated drug may counteract cardiovascular aging. 

Nicolas Musi, MD, professor of medicine and an author of the study (image: sanantoniomag.com). 

Cardiovascular

Model: Primary hippocampal neurons from non-transgenic C57BL/6 (nTg) and triple-transgenic 3xTg-AD mice; age groups: young (2–6 mo), middle (8–11 mo), and old (17–28 mo).
Dosage: Nicotinamide 2 mM + EGCG 2 µM applied to cultured neurons for 16 h (in vitro).

Study shows that brief nicotinamide + EGCG treatment restores neuronal energy in 16–24 hours, restores autophagy, reduces amyloid-beta buildup, and boosts neuron survival by ~22% in aging/Alzheimer’s lab models.

Brain &amp; Neurons

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

(The Buck Institute for Research on Aging | Facebook)

In a first-of-its-kind human trial, participants who underwent therapeutic plasma exchange exhibited significantly lowered biological age.

Amidst transparency issues, neuroscientists can only wonder if Neuralink will face the usual long-term problems of brain-computer interfaces.

Search Result: RNA Replacement

Bryan Johnson’s “Clone”: Where the Sci-Fi Ends and the Science Begins

Longevity Drug Rapamycin Improves the Heart of Older Adults, New Study Shows

Nicotinamide + EGCG Reboot Autophagy and Ease Hallmarks of Brain Aging

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

Elon Musk’s Neuralink: What’s Next After First Human Brain Implant?