Human studies show that a higher intake of the naturally occurring molecule spermidine may prevent cognitive impairments and dementia while improving longevity. 


Brain &amp; Neurons

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

How to counteract age-related gut microbe alterations through diet, lifestyle interventions, and supplements. 

Counteracting the aging microbiome with a fiber-rich diet and supplements. 

Dr. Mark Hyman, who developed 6-pack abs in his 60s, explains how he ages without disease, including following the Pegan diet — the best of a paleo and vegan diet. 

Longevity expert Dr. Mark Hyman got 6-pack abs in his sixties. To do this, he exercises regularly, practices relaxation techniques, and follows a diet that minimizes elevations in blood sugar levels. 

Based on human evidence, Harvard and MIT scientists determine the most promising anti-aging interventions, including NAD+ precursors, spermidine, and senolytics. 


MIT’s Leonard Guarente, Ph.D. (image: amacad.org), Harvard’s David Sinclair, Ph.D. (image: buckinstitute.org), and University of Paris Descartes’ Guido Kromer, Ph.D., M.D. (image: createcures.org). 

David Sinclair and fellow top aging biology researchers review clinical trials pertaining to the eight anti-aging compounds. 

Search Result: Probiotics

Spermidine: A Promising Nutrient for Brain Health and Cognitive Aging

Longevity Prescription

How to Improve Gut Microbiome Health with Age

6-Pack Abs at 60: Longevity Doc’s Diet

David Sinclair and Colleagues Summarize 8 Anti-Aging Medicines Applicable to Humans