Participants: healthy adults between the ages of 50 and 81
Dosage: 5 mg/week or 10 mg/week of rapamycin

One of the most potent anti-aging compounds rapamycin — an FDA-approved drug that inhibits mTOR — increases the lean body mass of older women while reducing their pain. 


Senior investigator Sajad Zalzala, MD (image: cnbc.com)

Clinical Trials

A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Aging &amp; Longevity

Model: 16-month-old female C57BL/6 mice 
Dosage: 60 mg/kg/day of ABT-263 dissolved in drinking water for 7 days on, 7 days off, and 7 days on again

A senolytic compound and anti-cancer drug called ABT-263 accelerates ovarian aging in aged mice, suggesting it promotes infertility. 

Others

Will Interventions that Delay Aging in Animals Work for Humans?

Researchers have shown that using certain agents targeting hallmarks of aging (like inflammation) can extend lifespan in mice, yet human trials are just beginning to uncover whether they work in humans.

(Aged individuals may benefit from aging interventions that work in animal models | NAD.com)

Harvard anti-aging expert Dr. David Sinclair says that low-dose Viagra has become popular, but why?


Some studies suggest that Viagra may treat Alzheimer's disease. 

Search Result: Lung Cancer

Anti-Aging Supplement Rapamycin Increases Muscle and Reduces Pain: New Results

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Which Anti-Aging Senolytic Supplement Should You Avoid?

Will Interventions that Delay Aging in Animals Work for Humans?

Taking Viagra to Improve Memory and Prevent Dementia