Does NAD+ (nicotinamide adenine dinucleotide) really help with aging? A team of international scientists reviews the latest and ongoing clinical trials.

Part of the research team, including Dr. Evandro Fei Fang (middle), from the University of Oslo and Akershus University Hospital in Norway (image: med.uio.no). 

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

An aging research aficionado, Dr. Josh Helman, shares five supplements that can help fight the effects of aging: nitric oxide, NMN, honokiol, modified citrus pectin, and creatine.

(Harvard-trained aging expert, Dr. Josh Helman | Jupiter Medical Center)

Harvard-trained aging expert Dr. Josh Helman unveils his top five supplements to fight against aging.

Aging &amp; Longevity

Model: Cybrids composed of Rho0 cells with human platelet mitochondrial DNA from participants between 7 days old and 99 years old 
Dosage: 5 mM of n-Acetyl-L-Cysteine and 3 mM of nicotinamide riboside, with medium changed every three days until the cell population reached between 1 and 10 million

New Study: Combining NR with NAC May Slow Telomere Shortening

New research suggests that nicotinamide riboside (NR) combined with N-acetyl cysteine (NAC) prevents telomere shortening linked to genetic sequences within the cell’s powerhouse (mitochondria) in human cells.

(Telomeres [highlighted in gold] at the ends of a chromosome | NAD.com)

A new study suggests the NAD+ precursor NR combined with the antioxidant NAC may counteract telomere shortening, a hallmark of aging.

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Participants: healthy adults between the ages of 50 and 81
Dosage: 5 mg/week or 10 mg/week of rapamycin

One of the most potent anti-aging compounds rapamycin — an FDA-approved drug that inhibits mTOR — increases the lean body mass of older women while reducing their pain. 


Senior investigator Sajad Zalzala, MD (image: cnbc.com)

Search Result: Lung Cancer

NAD+ and Aging: What the Latest Research Says

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

New Study: Combining NR with NAC May Slow Telomere Shortening

Longevity Prescription

Anti-Aging Drug Rapamycin Increases Muscle and Reduces Pain: New Results