Model: 699 European adults with an average age of 63.11 years

Longest Aging Clock Study to Date Shows Robust Improvement in Mortality Risk Prediction

A new study provides evidence that using aging clocks based on molecular tagging patterns on DNA (epigenetic aging clocks) to take multiple age readings across time outperforms taking single measurements in predicting mortality.

(The study’s principal investigator, Luigi Ferrucci | LinkedIn)

An Institute for Research on Aging study provides evidence that using epigenetic aging tests at multiple time points predicts mortality better than a single measurement.

Epigenetics

Model: C57BL/6J mice 
Dosage: Eating only within an 8-hour window and fasting for 16 hours (~20% caloric deficit may be required)

Restricting food intake for 16 hours a day improves the health of female mice and moderately prolongs the life of male mice. 

The principal investigators of the study (from left to right): Dr. Carla Green, Dr. Victoria Acosta-Rodriguez, and Dr. Joseph Takahashi (image: dallasnews.com). 

Aging &amp; Longevity

New Framework Uncovers 21 Existing Drugs with Pro-Longevity Potential

A new gene network-based framework predicts the potential of existing drugs to confer pro-longevity effects.

A new gene network-based framework predicts already-approved repurposable drugs that may either confer pro-longevity benefits or age-accelerating effects.

Model: SAMP8 mice 
Dosage: ~25 mg/kg/day of PQQ or PQI administered in food

Supplementing with the antioxidant pyrroloquinoline quinone (PQQ) modestly extends the lifespan of age-accelerated mice while improving their strength.  


Examining Evidence for the Cognition-Enhancing Potential of the Antioxidant Astaxanthin

The antioxidant astaxanthin significantly extends male mouse lifespan, and human research suggests it may help prevent age-related cognitive decline.

(An image of the red-orange pigment astaxanthin | Gruppo Farmalmpresa)

The potent antioxidant astaxanthin may have pro-longevity effects, and human trial data suggests it improves cognitive function in older adults.

Search Result: Longevity

Longest Aging Clock Study to Date Shows Robust Improvement in Mortality Risk Prediction

16-Hour Intermittent Fasting Improves Health and Longevity, New Study Confirms

New Framework Uncovers 21 Existing Drugs with Pro-Longevity Potential

Powerful Antioxidant PQQ Extends Life and Improves Strength, New Study Shows

Examining Evidence for the Cognition-Enhancing Potential of the Antioxidant Astaxanthin