Model: Chronically stressed mice 
Dosage: 9 mg/kg/day of L-serine, or 5 mg/kg/day of dasatinib combined with 50 mg/kg/day of quercetin

Supplementing chronically stressed mice with L-serine, an amino acid, counters signs of anxiety and diabetes while diverting age-promoting senescent cells within the brain’s fear center. 

Diabetes &amp; Obesity

Elevating the naturally occurring molecule NAD+ (nicotinamide adenine dinucleotide) improves memory and corrects gene-splicing patterns in a worm and a mouse model for dementia. 

Senior author on the study, Dr. Evandro Fang (front left), with some students (image: evandrofanglab.com)

Brain &amp; Neurons

Does NAD+ (nicotinamide adenine dinucleotide) really help with aging? A team of international scientists reviews the latest and ongoing clinical trials.

Part of the research team, including Dr. Evandro Fei Fang (middle), from the University of Oslo and Akershus University Hospital in Norway (image: med.uio.no). 

Participants: Healthy adults (18 to 47 years old)
Dosage: 1 g of an NAD+ precursor, 12.35 g of L-serine, 3.73 g of L-carnitine tartrate, and 2.55 g of N-acetyl cysteine

Of five different NAD+ precursors, NMN and NR similarly reduce blood fat levels and boost NAD+ levels when combined with an antioxidant and fat-burning blend, called the combined metabolic activator (CMA), in healthy adults.  


Discover the latest international study revealing the metabolic health effects of NMN and NR formulations. Explore the similarities and benefits of these NAD+ precursors for improving overall metabolic health.

NMN and NR Formulations Exert Similar Metabolic Health Effects: Latest International Study

Metabolism

Model: 22-month-old mice 
Dosage: Approximately 100 mg/kg/day D-serine in drinking water

The amino acid D-serine is reduced in older individuals, and D-serine supplementation improves the memory of aged mice. 


The hypothalamus of the brain controls many whole-organism functions. | shutterstock.com

Search Result: L-serine

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