Chinese scientists have genetically engineered stem cells capable of rejuvenating the health, including the cognition, of aged macaques. 

A young crab-eating macaque (image: shutterstock.com). 

Aging &amp; Longevity

Model: C57BL/6J mice, J20 mice, and 3xTg mice 
Dosage: 4.3 μEq l−1 of lithium in drinking water starting at 10 to 12 months of age and continued for 10 to 14 months during aging

Harvard Study: A Low Dose of Lithium May Preserve Cognitive Resilience with Age

Researchers uncover significantly lower brain lithium levels in Alzheimer’s disease patients, and supplementing with a low-dose lithium salt restores memory in an Alzheimer’s disease mouse model.

(The study’s principal investigator, Bruce Yankner [center], with four laboratory employees | The Boston Globe)

A Harvard study suggests lower levels of lithium in the brains of patients with Alzheimer’s disease and that lithium supplementation may help preserve cognitive resilience.

Brain &amp; Neurons

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

An aging research aficionado, Dr. Josh Helman, shares five supplements that can help fight the effects of aging: nitric oxide, NMN, honokiol, modified citrus pectin, and creatine.

(Harvard-trained aging expert, Dr. Josh Helman | Jupiter Medical Center)

Harvard-trained aging expert Dr. Josh Helman unveils his top five supplements to fight against aging.

99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

Despite his previous battles with alcoholism, Dick Van Dyke is approaching his 10th decade of life and serves as a beacon for preserving physical function into his golden years.

(At age 99, Dick Van Dyke still maintains a remarkable degree of physical function | NBC News)

At age 99, Dick Van Dyke avoids harmful foods, eats foods high in antioxidants, and keeps moving, a regimen that may have contributed to his astounding longevity.

Model: Cybrids composed of Rho0 cells with human platelet mitochondrial DNA from participants between 7 days old and 99 years old 
Dosage: 5 mM of n-Acetyl-L-Cysteine and 3 mM of nicotinamide riboside, with medium changed every three days until the cell population reached between 1 and 10 million

New Study: Combining NR with NAC May Slow Telomere Shortening

New research suggests that nicotinamide riboside (NR) combined with N-acetyl cysteine (NAC) prevents telomere shortening linked to genetic sequences within the cell’s powerhouse (mitochondria) in human cells.

(Telomeres [highlighted in gold] at the ends of a chromosome | NAD.com)

A new study suggests the NAD+ precursor NR combined with the antioxidant NAC may counteract telomere shortening, a hallmark of aging.

Search Result: Kidney disease

Anti-Aging Breakthrough: Stem Cells Reverse Signs of Aging in Monkeys

Harvard Study: A Low Dose of Lithium May Preserve Cognitive Resilience with Age

A Harvard-Trained Doctor’s Top 5 Anti-Aging Supplements

99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

New Study: Combining NR with NAC May Slow Telomere Shortening