Approved Human Study Sets Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

In a major proving ground test for the longevity field, the FDA has given its approval for a human trial for a gene therapy attempting a near-total rejuvenating reset of cells.

(David Sinclair, Michael Ringel, Sharon Rosenzweig-Lipson, and Jerry McLaughlin of Life Biosciences | Longevity.technology)

The FDA has greenlighted Life Biosciences’ first human trial testing whether their gene therapy can confer a near-total rejuvenating reset of cells.

Clinical Trials

Anti-Aging Breakthrough? Harvard's David Sinclair Predicts Age-Reversing Pill by 2035

A leading thinker in the field of aging research, Dr. David Sinclair, shares insights on the rapid pace of advancements in aging research and predicts the availability of age-reversing pills within the next 10 years.

(Dr. David Sinclair believes an age-reversing pill is under development | YouTube)

Harvard’s Dr. David Sinclair believes an age-reversing pill may become available within a decade and that researchers may find a way to one day double human lifespan.

Aging &amp; Longevity

<p>Model: Sprague Dawley rats</p>
<p>Dosage (oral): 500 mg/kg of nicotinamide in drinking water</p>


Vitamin B₃ Alleviates Diabetes-Induced Eye Degeneration 

Korean scientists show that vitamin B₃ reduces retinal deterioration by reducing DNA damage in a rat model for diabetes. 


Metabolism

Scientists restore eyesight in mice with glaucoma and age-related visual impairment by delivering youth-promoting genes. 

Harvard scientists restore eyesight in eye cells of mice with glaucoma and age-related vision loss by delivering embryonic genes.

How Genes Affect Vision in Old Age

Epigenetics

The addition of Disarm's promising programs for axonal degeneration expands Eli Lilly and Company’s R&D efforts in pain and neurodegeneration.

Eli Lilly acquires Disarm Therapeutics, a pharmaceutical company with programs to counter axonal degeneration and neurodegeneration.

Search Result: Glaucoma

FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

Anti-Aging Breakthrough? Harvard’s David Sinclair Predicts Age-Reversing Pill by 2035

Korean Study Shows Vitamin B₃ Alleviates Diabetes-Induced Eye Degeneration

Reversing Age-Related Vision Loss with Embryonic Gene Delivery

Lilly Lands Disarm Therapeutics and NAD⁺ Metabolism Drug to Fight Neurological Diseases