Model: 8 adults with peripheral artery disease 
Dosage: 1,000 mg of NR daily for four weeks

New Study Suggests NR Modestly Improves Cognition in Age-Related Vascular Disease

Taking NR was associated with improved blood flow to a specific brain region following cognitive stimulation, as well as trends toward enhanced cognition in patients with age-related vascular disease.

(The study’s principal investigator, Andriy Yabluchanskiy | LinkedIn)

Taking NR is associated with improved blood perfusion to a brain region involved in memory and daily task organization, as well as a trend toward enhanced cognition.

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

Supplementing with 20 grams of creatine improves the cognition of individuals with Alzheimer’s disease. 

Brain &amp; Neurons

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


Model: Healthy adults between 21 and 79 years of age 
Dosage: 395 mg/kg of bodyweight of (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate monoester (𝛽-hydroxybutyrate ketones) diluted in water and administered once

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

A new study suggests that supplementing with ketones—molecules the body can use for energy when lacking sugars—prevents cognitive aging when administered in people’s 40s and 50s.

(The study’s principal investigator, Dr. Lilianne R. Mujica-Parodi | Stony Brook University News)

Based on age-related destabilized brain signaling, a new study suggests a critical midlife window where metabolic interventions may stabilize brain signaling.

Search Result: Cognition

New Study Suggests NR Modestly Improves Cognition in Human Subjects

Longevity Prescription

Creatine Supplement Improves Memory in People with Alzheimer’s: New Pilot Study

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging