Model: Male C57BL/6 mice given continuous alcohol for 4 weeks 
Dosage: 350 mg/kg/day of nicotinamide riboside chloride for 2 weeks

The NAD+ (nicotinamide adenine dinucleotide) precursor nicotinamide riboside chloride (NRC) counteracts neuronal damage caused by alcohol consumption in mice. 

Brain &amp; Neurons

Innovative Computer Model Reveals Aging May Stem from Lost Cellular Purpose

A new computer simulation suggests aging occurs when cells and tissues lose their developmental goals, offering a fresh perspective on rejuvenation strategies.

(The article’s principal investigator, Michael Levin | Tufts Now)

An innovative computer model simulates aging, suggesting that cells and tissues lose their developmental goals, leading to physiological deterioration.

Aging &amp; Longevity

Model: Male Sprague-Dawley rats 
Dosage: 400 mg/kg of magnesium L-theanine and 600 mg/kg of nicotinamide riboside administered orally for 40 days

Scientists find that treating rats with magnesium L-theanine and nicotinamide riboside (NR) counteracts stress-induced metabolic, gut, and liver aging. 

Study conducted by researchers from Firat University in Turkey (image: turkeyuniversity.org)

Participants: Healthy males (age range: 70-76)
Dosage: 1 mg/kg/day of rapamycin for 8 weeks

Supplementing with rapamycin leads to improvements in cardiac and vascular function in older men, suggesting this longevity-associated drug may counteract cardiovascular aging. 

Nicolas Musi, MD, professor of medicine and an author of the study (image: sanantoniomag.com). 

Cardiovascular

Model: Aged mice (18 months old) underwent exploratory laparotomy under isoflurane anesthesia to induce POCD.
Dosage: Berberine was given by oral gavage at 100 mg/kg per day for 14 days after surgery.

Ancient Plant Compound Shows Promise for Protecting the Aging Brain 

Study shows berberine, a natural plant compound, protects memory in aging mice after surgery by reducing brain inflammation, stress, and cell damage.


Search Result: research findings

NAD+ Supplement Counters Alcohol-Induced Brain Aging, According to New Study

Innovative Computer Model Reveals Aging May Stem from Lost Cellular Purpose

New Research: Magnesium, L-Theanine, NAD+ Combo Counters Stress Aging

Longevity Drug Rapamycin Improves the Heart of Older Adults, New Study Shows

Ancient Plant Compound Shows Promise for Protecting the Aging Brain