San Francisco scientists find that the FDA-approved drug octreotide, a growth hormone inhibitor, may restore processing speed and mental agility in aged beagles.

Brain &amp; Neurons

Model: Otherwise healthy adults aged 40 and older
Dosage: 15 g of the multi-ingredient supplement dissolved in up to 500 mL of water or juice, given each day orally for six months

Can a Nutritional Supplement Prevent Vascular Aging? 6-Month Human Trial Results

A six-month human trial found that a multi-ingredient nutritional supplement improved vascular health, reducing arterial stiffness and lowering systolic blood pressure.

(An image depicting increased arterial stiffness [measured with pulse-wave velocity] and blood pressure, along with reduced flow-mediated dilation in aged blood vessels | NAD.com)

A six-month randomized trial found that a multi-ingredient supplement improved vascular health markers, including arterial stiffness and blood pressure.

Cardiovascular

Model: 20-month-old C57BL/6N male mice (roughly equivalent to 60-year-old humans)
Dosage: 8,000 mg/kg of taurine administered daily via oral gavage for four months

Yale Study Shows How Taurine Reduces Age-Related Inflammation

A new study reveals how taurine helps curb age-related inflammation in aged mice by targeting a key inflammatory pathway in immune cells.

A new study finds that taurine supplementation reduces signs of inflammation and improves some measures of physical function in aged male mice.

Aging &amp; Longevity

A new U.S. Army study shows that waist circumference and belly fat are far stronger determinants of circulating testosterone levels than aging.


An image from a previous publication authored by Dr. Karl E. Friedl, one of the U.S. Army scientists on the current study. 

Model: Apoe−/− C57BL/6J mice fed a high-fat diet
Dosage: 1 × 109 CFU per 0.1 mL of Bacteroides uniformis administered to mice via oral gavage for 12 weeks and 25 mg/kg of pentadecanoic acid via oral gavage three times per week for eight weeks

New Study: Gut Bacteria Metabolite Reduces Arterial Plaque Burden by 50%

Researchers identified pentadecanoic acid, a gut-bacteria-produced metabolite, that lowered LDL cholesterol and limited arterial plaque buildup in mice.

(A depiction of various gut bacteria in the intestines | NAD.com)

A gut bacterial metabolite reduced arterial plaque buildup by about 50% in mice, revealing a potential link between gut microbes and cholesterol regulation.

Search Result: metabolic health

Growth Hormone Blocker Sharpens Thinking in Aging Dogs, New Study Finds

Can a Nutritional Supplement Prevent Vascular Aging? 6-Month Human Trial Results

Yale Study Shows How Taurine Reduces Age-Related Inflammation

Why Low Testosterone Isn’t Just About Getting Older: New U.S. Army Findings Point to Belly Fat

New Study: Gut Bacteria Metabolite Reduces Arterial Plaque Burden by 50%