The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

According to French scientists, no organ system appears as vulnerable to aging as the cardiovascular system, and anti-aging therapeutics may help mitigate the effects of cardiovascular disease.

(The principal investigator behind the review, aging researcher Guido Kroemer | Olympiad in Cardiovascular Medicine)

Anti-aging therapeutics may prevent and slow age-related cardiovascular dysfunction.

Cardiovascular

Model: UM-HET3 Mice 
Dosage: 0, 75, 150, 300, 600, and 1200 ng epicatechin/mg food; 0, 0.075, 0.15, 0.3, 0.6, and 1.2 ng halofuginone/mg food; and 0, 37.5, 75, 150, 300, and 600 ng mitoglitazone/mg food, all given ad libitum in food starting at seven months old

Three Compounds Show Promise for Male Longevity

Data from a rigorous longevity study show promise for three new compounds, adding to the repertoire of mouse lifespan-extending substances.

(The three compounds’ effects on median lifespan extension | Rapamycin Longevity News)

The world’s most rigorous longevity study presents data showing promise for three new lifespan-extending compounds in male mice.

Aging &amp; Longevity

α-Lipoic Acid: Efficacy, Safety, and Dosage

α-lipoic acid is an antioxidant naturally produced by the body, which is also available as a supplement, and human trials indicate that it has neuroprotective and male fertility-enhancing effects.

(α-lipoic acid’s molecular structure | Neuroneeds)

α-lipoic acid is a potent antioxidant, which human trials suggest has neuroprotective and male fertility-enhancing properties.

Metabolism

Three types of beer, including IPA and stout, are shown to improve indicators of metabolic health in a mouse model for aging. 

Participants: Healthy older adults 
Dosage: 1 mg/day of rapamycin for 8 weeks

Older adults taking low-dose rapamycin exhibit a reduction in senescent cells — cells that contribute to age-related diseases and a shorter lifespan. 

Associate professor at Oxford University and corresponding author on the study, Lynne S Cox, MA, PhD (image: researchgate.com).

Search Result: metabolic benefits

The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

Three Compounds Show Promise for Male Longevity

An Overview of α-Lipoic Acid: Efficacy, Safety, and Dosage

Scientists Claim Beer Counters Age-Related Metabolic Decline in New Study

New Oxford Study: Powerful Longevity Drug Rapamycin Targets Cell Senescence