Advanced Alzheimer’s Can Be Reversed With NAD+ Restoration, Study Shows in Mice

Researchers at Case Western Reserve University have shown that late-stage neurodegeneration may be biologically reversible, at least in the right conditions, in mice.

(Case Western Reserve University | Cleveland 19)

Brain &amp; Neurons

Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Immunity

A molecule found in the plasma of exercised mice reverses the brain aging of sedentary mice. 

(Image: UCSF.edu) Senior author Saul Villeda, PhD. 

Model: 24-month-old female Sprague Dawley rats
Dosage: Undisclosed doses of pig-derived exosomes were injected into the rats every-other-day for eight days starting at day 1 and recommencing at days 68, 181, 280, and 377

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

Nano-sized vesicles called exosomes derived from pig blood plasma significantly extended rat lifespan and broke the record for the longest-living rat.

(An image of Sima, the longest-recorded living rat, at 47 months of age | The Guardian)

Aging &amp; Longevity

Model: Twenty-five-month-old female Sprague-Dawley rats
Dosage: 1 mL of blood plasma from two-month-old rats intraperitoneally injected every other week until death
Model: C57BL/6J male mice
Dosage: 0.055 mg/mL of ergothioneine administered orally in water from seven weeks of age until death

Canadian Longevity Organization Spotlights Key Research on Latest Anti-Aging Treatments

The Canadian Longevity Association — a non-profit organization dedicated to accelerating longevity research — highlights research on rodent lifespan extension with young plasma and the mushroom-derived compound ergothioneine.

(Canadian Longevity Association | Facebook)

The Canadian Longevity Association presents new findings showing that injecting young plasma into older individuals and mushroom-derived ergothioneine extend lifespan in rodents.

Search Result: Young Plasma

Advanced Alzheimer’s Can Be Reversed With NAD+ Restoration, Study Shows in Mice

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Scientists Identify a Molecule that Mimics the Anti-Aging Effects of Exercise on the Brain

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

Canadian Longevity Organization Spotlights Key Research on Young Plasma and Mushroom-Based Anti-Aging Treatments