Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Immunity

A molecule found in the plasma of exercised mice reverses the brain aging of sedentary mice. 

(Image: UCSF.edu) Senior author Saul Villeda, PhD. 

Model: 24-month-old female Sprague Dawley rats
Dosage: Undisclosed doses of pig-derived exosomes were injected into the rats every-other-day for eight days starting at day 1 and recommencing at days 68, 181, 280, and 377

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

Nano-sized vesicles called exosomes derived from pig blood plasma significantly extended rat lifespan and broke the record for the longest-living rat.

(An image of Sima, the longest-recorded living rat, at 47 months of age | The Guardian)

Aging &amp; Longevity

Model: Twenty-five-month-old female Sprague-Dawley rats
Dosage: 1 mL of blood plasma from two-month-old rats intraperitoneally injected every other week until death
Model: C57BL/6J male mice
Dosage: 0.055 mg/mL of ergothioneine administered orally in water from seven weeks of age until death

Canadian Longevity Organization Spotlights Key Research on Latest Anti-Aging Treatments

The Canadian Longevity Association — a non-profit organization dedicated to accelerating longevity research — highlights research on rodent lifespan extension with young plasma and the mushroom-derived compound ergothioneine.

(Canadian Longevity Association | Facebook)

The Canadian Longevity Association presents new findings showing that injecting young plasma into older individuals and mushroom-derived ergothioneine extend lifespan in rodents.

The Cleveland Clinic’s Dr. Michael Roizen Says Age 90 May Become the New 40

Dr. Michael Roizen, the Chief Wellness Officer at the Cleveland Clinic, believes there is an 80% probability of aging interventions making 90-year-olds 40 again within the next decade.

(Dr. Michael Roizen, the Cleveland Clinic’s Chief Wellness Officer | YouTube)

The Cleveland Clinic’s Chief Wellness Officer, Dr. Michael Roizen, believes there is an 80% probability of making 90-year-olds 40 again via new longevity interventions developed in the next decade.

Search Result: Young Plasma

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Scientists Identify a Molecule that Mimics the Anti-Aging Effects of Exercise on the Brain

Nano-Sized Vesicle Infusions Break Rat Lifespan Record

Canadian Longevity Organization Spotlights Key Research on Young Plasma and Mushroom-Based Anti-Aging Treatments

The Cleveland Clinic’s Dr. Michael Roizen Says Age 90 May Become the New 40