<p>Model: 20-month-old female C57BL/J mice </p>
<p>Dosage: 10 nmol/kg/day of semaglutide </p>


Semaglutide extends mouse lifespan and targets signs of aging, such as diminished NAD+, while mimicking the anti-aging effects of caloric restriction (consuming fewer calories). 


The study was led by Dr. Danica Chen (image: berkeley.edu). 

Aging &amp; Longevity

Top Evidence-Based Interventions to Lower Biological Age

Epigenetic aging clocks estimate biological age based on DNA molecular tagging patterns, and interventions like semaglutide and ketamine reduce these estimates in humans.

(The principal investigator behind the review on interventions that influence biological age, Dr. David Sinclair | The Society of the Four Arts)

As reviewed in this article, epigenetic aging clocks have estimated the effects of pharmaceutical interventions, lifestyle habits, supplements, and clinical interventions on biological age.

Wegovy is now FDA-approved to lower the risk of mortality from heart disease, but not everyone may benefit. 


Popular weight loss drug reduces risk of death from heart disease. 

Cardiovascular

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest "Longevity Drug" Seragon RESTORIN Make the List 

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon RESTORIN. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon Restorin. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Search Result: Semaglutide

Semaglutide (Ozempic) Enhances the Most Powerful Driver of Longevity & Boosts NAD+ in Mice, New Study Shows

Top Evidence-Based Interventions to Lower Biological Age

FDA Approves Drug Similar to Ozempic for Reducing Heart Disease Risks: The New Antidote to Aging?

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest “Longevity Elixir” Seragon RESTORIN Make the List