New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

Fayoum University researchers found that cranberry polyphenols improve metabolic markers, cognition, and oxidative stress to the same degree as the drug metformin.

A new study suggests cranberry extract has effects against aging that rival metformin.

Aging &amp; Longevity

Participants: Adults over the age of 60
Dosage: 3,750 mg of niacin twice daily (after gradual dose increase), 150 mg of dihydroberberine twice daily, 50 mg of taxifolin (with 500 mg of vitamin C and 15 mg of zinc) twice daily, 50 mg of tocotrienols twice daily

A combination of supplements, including the NAD+ precursor nicotinic acid, improves cholesterol, allowing some participants to cease taking statins.  

Study conducted by Professor Emeritus Joseph Keenan, MD, at the University of Minnesota. 

Nicotinic Acid

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


Model: Two-month-old male C57BL/6J mice fed a high-fat diet to induce obesity 
Dosage: 400 mg/kg/day of NR for eight weeks

Scientists find that NR (nicotinamide riboside) supplementation preserves brown fat tissue in mice, reducing their body weight and maintaining the health of their mitochondria. 

An artist’s rendering of a brown fat cell (image: Alioui Ma/shutterstock.com). 

Diabetes &amp; Obesity

Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years

Worldwide, people consume about 2 billion cups of coffee a day, and a new review associates drinking this caffeinated beverage regularly with an average of 1.8 years added to lifespan.

Search Result: Metabolic syndrome

New Study Shows Cranberry Extract Equivalent to Metformin in Fighting Aging

NAD+ Boosting Supplement Challenges Cholesterol-Lowering Statins in Anti-Aging Research

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol

NAD+ Precursor NR Preserves Longevity-Promoting Cells, New Study Shows

Cumulative Research Suggests Coffee Prolongs Life by 1.8 Years