German researchers discover rare genetic mutations related to the mTOR pathway in the DNA of long-lived individuals. 

Aging &amp; Longevity

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Ranked fourth on the Rejuvenation Olympics leaderboard, 30-year-old Siim Land lists the supplements he takes to stay young. 


The claims of the study in question run contrary to a collection of previous studies, where heart disease risk was actually measured. 

Study has prompted overhyped headlines on news outlets like Newsweek and the New York Post and a high protein diet likely does not increase heart disease risk. 

Cardiovascular

<p>Model: HET3 mice, which are genetically heterogenous to model the diversity of human genetics more precisely than other lab mice, which are usually genetically homogenous </p>
<p>Dosage: 67% reduction in dietary intake of isoleucine </p>


Limiting dietary intake of the amino acid — protein building block — isoleucine significantly extends the lifespan of male mice and modestly extends the lifespan of female mice. 


Search Result: Leucine

Longevity Secrets in Your Genome: Hidden mTOR Variants Identified

Longevity Prescription

Fourth Slowest Ager in World Siim Land’s 2025 Longevity Supplement Protocol

New Study Claims High Protein Foods Increase Heart Disease Risk — Don’t Believe the Hype

Study Shows Avoiding Consumption of Protein Building Block Isoleucine Increases Lifespan