Approved Human Study Sets Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

In a major proving ground test for the longevity field, the FDA has given its approval for a human trial for a gene therapy attempting a near-total rejuvenating reset of cells.

(David Sinclair, Michael Ringel, Sharon Rosenzweig-Lipson, and Jerry McLaughlin of Life Biosciences | Longevity.technology)

The FDA has greenlighted Life Biosciences’ first human trial testing whether their gene therapy can confer a near-total rejuvenating reset of cells.

Clinical Trials

Participants: Physically active and healthy older adults 
Dosage: 1 gram of omega-3s (330 mg EPA plus 660 mg DHA) per day, 2,000 IU of vitamin D per day, and 30 minutes of strength training exercises three times per week

While omega-3 supplementation slows biological aging, adding vitamin D and exercise further slows biological aging.

The “father of aging clocks” and senior study author Steve Horvath, PhD, of Harvard University (Image: quantamagazine.org). 

Aging &amp; Longevity

The Dementia Surge: New Study Projects Cases to Double by 2060

Researchers project dementia cases in the U.S. to double by 2060, revealing higher incidence in women, Black adults, and APOE ε4 carriers

Brain &amp; Neurons

Model: C57BL/6J mice
Dosage: 500 mg/kg/day of Urolithin A in food

Supplementing with urolithin A prevents age-related hearing loss and mitochondrial dysfunction in mice. 

Is Hyperbaric Oxygen Therapy A Rip-off?

Many longevity clinics are popping up across the world, and celebrities are promoting the lifespan-extension fad, sometimes for up to tens of thousands of dollars.

(A woman undergoing hyperbaric oxygen therapy | Northwestern Medicine)

Search Result: hearing

FDA Greenlights Life Biosciences’ Human Study, Setting Up Pivotal Test for Aging Theory from Harvard’s David Sinclair

Harvard Study Reveals that Omega-3s, Vitamin D, and Exercise Additively Slow Biological Aging

The Dementia Surge: New Study Projects Cases to Double by 2060

Urolithin A Anti-Aging Supplement Prevents Hearing Loss, New Research Shows

Is Hyperbaric Oxygen Therapy A Rip-off?