Participants: Healthy older adults 
Dosage: 1 mg/day of rapamycin for 8 weeks

Older adults taking low-dose rapamycin exhibit a reduction in senescent cells — cells that contribute to age-related diseases and a shorter lifespan. 

Associate professor at Oxford University and corresponding author on the study, Lynne S Cox, MA, PhD (image: researchgate.com).

Immunity

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

The longevity biotech company, MetaShape, has a new compound designed to restore cellular nicotinamide adenine dinucleotide (NAD+) and offset elevated cholesterol, cognitive decline, and neurodegeneration.

Model: Mouse
Dosage: 100 mg/kg sesamol
Administration: Dissolved in food

Sesame Seed Compound Prevents Weight Gain and Improves Metabolism

Chinese scientists find that sesamol treatment prevents signs of obesity, including weight gain and metabolic dysfunction, by activating AMPK and SIRT1 in middle-aged mice. 

Search Result: glucose intolerance

New Oxford Study: Powerful Longevity Drug Rapamycin Targets Cell Senescence

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

Study Shows Sesamol Prevents Weight Gain and Improves Metabolism in Middle-Aged Mice