Columbia University scientists find that inflammation increases the risk of common chronic age-related diseases only in people from industrialized populations. 

Columbia University in New York City (image: Columbia.edu). 

Immunity

<p>Model: 24-month-old male C57BL/6J mice </p>
<p>Dosage: 1% w/v of betaine for three weeks </p>


The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

Johns Hopkins Research Review: Parkinson’s Drug Extends Multiple Species' Lifespan

L-deprenyl, a drug used to treat Parkinson’s disease and major depressive disorder, has been shown to modestly extend lifespan across species, from mice to rats to hamsters.

L-deprenyl, a drug prescribed to treat Parkinson’s disease and major depressive disorder, has been shown to modestly extend average lifespan across mammalian model organism species.

Aging &amp; Longevity

<article class="text-token-text-primary w-full focus:outline-none [--shadow-height:45px] has-data-writing-block:pointer-events-none has-data-writing-block:-mt-(--shadow-height) has-data-writing-block:pt-(--shadow-height) [&amp;:has([data-writing-block])&gt;*]:pointer-events-auto [content-visibility:auto] supports-[content-visibility:auto]:[contain-intrinsic-size:auto_100lvh] scroll-mt-[calc(var(--header-height)+min(200px,max(70px,20svh)))]" dir="auto" tabindex="-1" data-turn-id="request-68faafe5-c214-8328-a645-d982c8e85808-32" data-testid="conversation-turn-56" data-scroll-anchor="true" data-turn="assistant">
<div class="text-base my-auto mx-auto pb-10 [--thread-content-margin:--spacing(4)] thread-sm:[--thread-content-margin:--spacing(6)] thread-lg:[--thread-content-margin:--spacing(16)] px-(--thread-content-margin)">
<div class="[--thread-content-max-width:40rem] thread-lg:[--thread-content-max-width:48rem] mx-auto max-w-(--thread-content-max-width) flex-1 group/turn-messages focus-visible:outline-hidden relative flex w-full min-w-0 flex-col agent-turn" tabindex="-1">
<div class="flex max-w-full flex-col grow">
<div class="min-h-8 text-message relative flex w-full flex-col items-end gap-2 text-start break-words whitespace-normal [.text-message+&amp;]:mt-1" dir="auto" data-message-author-role="assistant" data-message-id="4886ec11-c716-4535-bbf9-133201ac8d7a" data-message-model-slug="gpt-5">
<div class="flex w-full flex-col gap-1 empty:hidden first:pt-[1px]">
<div class="markdown prose dark:prose-invert w-full break-words light markdown-new-styling">
<p data-start="97" data-end="197">Model: Aged mice (18 months old, C57BL/6 strain) and aged rhesus macaques (18–21 years old).</p>
<p data-start="97" data-end="197">Dosage: Mice received 100 µg of EVs^ABPC via tail vein injection twice per week for 4 weeks.<br data-start="297" data-end="300" data-is-only-node="" />Rhesus macaques received 200 µg/kg of EVs^ABPC intravenously once per week for 20 weeks.</p>
</div>
</div>
</div>
</div>
<div class="z-0 flex min-h-[46px] justify-start"></div>
<div class="mt-3 w-full empty:hidden">
<div class="text-center"></div>
</div>
</div>
</div>
</article>
<div class="pointer-events-none h-px w-px" aria-hidden="true" data-edge="true"></div>


Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

Researchers discover that deer antler stem cells can restore bone density, slow aging, and reverse biological age in mice and primates.

<p>Model: Male C57BL/6 mice given continuous alcohol for 4 weeks </p>
<p>Dosage: 350 mg/kg/day of nicotinamide riboside chloride for 2 weeks </p>


The NAD+ (nicotinamide adenine dinucleotide) precursor nicotinamide riboside chloride (NRC) counteracts neuronal damage caused by alcohol consumption in mice. 

Search Result: biological aging

The Inflammation Myth: New Insights on Aging

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Johns Hopkins Research Review: Parkinson’s Drug Shown to Extend Lifespan Across Mammalian Species

Scientists Discover Deer Antler Stem Cells That Reverse Aging in Mice and Monkeys

NAD+ Supplement Counters Alcohol-Induced Brain Aging, According to New Study