Japanese scientists have found that reducing NAD+ (nicotinamide adenine dinucleotide) transport into mitochondria within the fat tissue of mice induces metabolic dysregulation and obesity. 

Participants: Prefrail older adults
Dosage: 50 mg/day of losartan for at least 8 weeks

Losartan, a common blood pressure medication, increases the survival rate of mice and improves the metabolic outlook of pre-frail older adults. 

Principal Investigator of the study, Dr. Peter M. Abadir (image: jhu.edu).

Aging &amp; Longevity

David Attenborough Turns 100: 5 Longevity Habits of the Renowned British Broadcaster

David Attenborough’s longevity secrets encompass simple practices, such as walking, eating plant foods, spending time in nature, and maintaining social connections.

David Attenborough’s longevity secrets include not eating much meat, having a sense of purpose, eating small meals, spending time in nature, and maintaining social connections.

Peter Fedichev’s Physics-Based Approach to Aging: A New Longevity Framework

Peter Fedichev describes aging as a three-variable system of stress (from physical, psychological, or molecular stressors), noise (small random biological fluctuations), and damage (cumulative wear-and-tear).

Peter Fedichev has proposed a physics-based framework for aging, encompassing stress, noise (small random biological fluctuations), and damage (cumulative wear-and-tear).

Participants: Sedentary older adults 
Dosage: 6 mg/week of rapamycin

In older adults, the FDA-approved drug rapamycin, associated with prolonging lifespan, blunts improvements in physical performance.

Search Result: anti aging

NAD+ Transporter Prevents Obesity Caused by Aging: New Study Shows

New Johns Hopkins Study: FDA-Approved Losartan May Extend Lifespan

David Attenborough Turns 100: 5 Longevity Habits of the Renowned British Broadcaster

Peter Fedichev’s Physics-Based Approach to Aging: A New Longevity Framework

Rapamycin and Exercise: New Study Finds Potential Performance Decline