Model: Young C57BL/6J mice fed a high protein (56% of daily calories) diet for 20 weeks 
Dosage: Injection with either 400 mg/kg of NMN or 20 mg/kg of 78c for 4 weeks

High protein intake improves the body composition of aged mice, but it lowers NAD+ (nicotinamide adenine dinucleotide) levels and promotes metabolic aging. 

Metabolism

Participants: Healthy male adults between the ages of 18 and 50 
Dosage: 714 mg/day of nicotinamide and 19 mg/day of pyridoxine for nine days

In a randomized human trial, combining nicotinamide with vitamin B6 increases stem cell activation and muscle-growth capacity in response to exercise. 

Skin &amp; Muscle

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

The most comprehensive brain model reveals that combining NAD+ (nicotinamide adenine dinucleotide) supplementation with diet and exercise powerfully modulates brain aging. 


Want to Get Fit? Look at What Sylvester Stallone Does at 78

Sylvester Stallone’s daily diet includes egg whites as well as broiled chicken and fish for plenty of protein, and his most current workouts focus on the chest, back, abs, and legs for optimal longevity.

(Even at age 78, Sylvester Stallone maintains a strikingly cut physique | YouTube)

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High Protein Intake Promotes Aging by Lowering NAD+ Levels

NAD+ Booster and Vitamin B6 Activate Stem Cells to Counter Muscle Shrinkage, New Studies Show

Longevity Prescription

Most Comprehensive Study Places NAD+ at Forefront of Countering Brain Aging

Want to Get Fit? Look at What Sylvester Stallone Does at 78