Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

Longevity guru Bryan Johnson shares his routine for perfect oral health. 


Bryan Johnson reveals his oral health routine. 

Poor sleep, encompassing insufficient sleep duration and poor sleep quality, increases mortality and chronic disease risks, which may be countered by specific lifestyle optimization tactics. 


Explore the potential impact of inadequate sleep on lifespan and delve into a comprehensive examination of the associated longevity risks. Discover the latest insights and research findings on the crucial role of quality sleep in overall health and longevity. Read more on NAD.

Potential Impact of Inadequate Sleep on Lifespan: A Closer Look at Longevity Risks - NAD

Longevity Interventions for Age-related DNA Changes

Epigenetics – changes to DNA expression rather than alteration of the DNA itself – may be the new frontier for anti-aging interventions, with researchers and doctors uncovering the ways in which epigenetics regulate age-related diseases and developing therapies to target these epigenetic changes.


B6 congenic 5XFAD 4-month-old mice
Wildtype B6 mice
100 µL F. nucleatum
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Gum Disease May Increase Alzheimer’s Risk

Researchers show that the oral pathogen Fusobacterium nucleatum (F. nucleatum) decreases cognitive function and exacerbates Alzheimer's features in mice modeling Alzheimer's. 

Oral bacteria F. nucleatum may escalate Alzheimer's progression, linking gum disease to increased cognitive decline, brain inflammation, and Alzheimer's markers.

Search Result: Oral hygiene

Longevity Prescription

Bryan Johnson’s Free Guide to Oral Hygiene: Toothpaste and All

Potential Impact of Inadequate Sleep on Lifespan: A Closer Look at Longevity Risks

Longevity Interventions for Age-Related DNA Changes

Gum Disease Pathogen Fusobacterium nucleatum May Increase Alzheimer’s Risk