Joe Rogan’s Top Supplements for 2026

Joe Rogan’s latest supplement stack includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

(Joe Rogan on set for his podcast | Spotify Newsroom)

Joe Rogan’s updated supplement stack for 2026 includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

Aging &amp; Longevity

Model: Healthy adults between 21 and 79 years of age 
Dosage: 395 mg/kg of bodyweight of (R)-3-hydroxybutyl-(R)-3-hydroxybutyrate monoester (𝛽-hydroxybutyrate ketones) diluted in water and administered once

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

A new study suggests that supplementing with ketones—molecules the body can use for energy when lacking sugars—prevents cognitive aging when administered in people’s 40s and 50s.

(The study’s principal investigator, Dr. Lilianne R. Mujica-Parodi | Stony Brook University News)

Based on age-related destabilized brain signaling, a new study suggests a critical midlife window where metabolic interventions may stabilize brain signaling.

Brain &amp; Neurons

Exploring Longevity Drugs in an Era of Slumping Investments and Rising Doubt

Venture capitalists have put the brakes on investments in longevity-related interventions over the past few years, yet experts predict new drug approvals will spur a funding surge.

Despite slumping investments in longevity-related biotech companies over the last few years, experts predict a funding surge as new therapies get closer to approval.

Industry

Model: APP-KI mouse model for Alzheimer’s disease
Intervention: Restricting feeding times within a 6-hour window each day for 3 months.

Intermittent Fasting Blocks Alzheimer’s Disease 

By restricting the feeding of Alzheimer’s model mice to 6 hours a day (18 hours of fasting), scientists prevent memory loss and counter brain pathology. 


Principal Investigator Dr. Paula Desplats | Desplats Lab 

Discover the groundbreaking research from UC San Diego demonstrating how intermittent fasting improves memory and alleviates brain pathology in Alzheimer's disease. Explore the implications of this study at NAD.

Search Result: Ketones

Joe Rogan’s Top Supplements for 2026

New Study Finds Midlife May Be a Critical Window to Prevent Brain Aging

Exploring Longevity Drugs in an Era of Slumping Investments and Rising Doubt

Intermittent Fasting Improves Memory and Rescues Brain Pathology in Alzheimer’s: UC San Diego Study