Model: Male Sprague-Dawley rats 
Dosage: 400 mg/kg of magnesium L-theanine and 600 mg/kg of nicotinamide riboside administered orally for 40 days

Scientists find that treating rats with magnesium L-theanine and nicotinamide riboside (NR) counteracts stress-induced metabolic, gut, and liver aging. 

Study conducted by researchers from Firat University in Turkey (image: turkeyuniversity.org)

Three types of beer, including IPA and stout, are shown to improve indicators of metabolic health in a mouse model for aging. 

Metabolism

Model: Naturally aged C57BL/6J mice

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

A new study provides data suggesting compromised intestinal function with age and that fasting for short periods promotes intestinal regeneration and function in aged mice.

(A dysfunctional intestinal barrier that leaks harmful substances and bacteria into circulation develops with age | The Amino Company)

Alternate-day fasting, a form of intermittent fasting, reverses age-related intestinal barrier leakage in old mice.

Aging &amp; Longevity

The cutoff for vitamin B12 deficiency is too low, according to new findings showing that “normal” B12 levels are associated with neurological deficits in older adults. 


Senior investigator, Ari Green, MD (image: ucsfhealth.org). 

Brain &amp; Neurons

Model: 18-month-old C57BL/6J mice 
Dose (oral): 5 mg/kg of dasatinib combined with 50 mg/kg of quercetin

Senolytics Restore Age-Related Heart-Brain Connection Loss

Treating old mice with two senolytics — compounds that remove senescent (dysfunctional) cells —  called dasatinib and quercetin prevents heart-brain connection loss and irregular heart rhythms.  


Principal Investigator Dr. Stefanie Dimmeler | DZHK 

Search Result: Intestinal Lining

New Research: Magnesium, L-Theanine, NAD+ Combo Counters Stress Aging

Scientists Claim Beer Counters Age-Related Metabolic Decline in New Study

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

Latest Study Finds Recommended Vitamin B12 Dose Is Wrong: How to Get Enough

German Study Shows Senolytics Restore Heart-Brain Connection to Reverse Cardiac Aging