99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

Despite his previous battles with alcoholism, Dick Van Dyke is approaching his 10th decade of life and serves as a beacon for preserving physical function into his golden years.

(At age 99, Dick Van Dyke still maintains a remarkable degree of physical function | NBC News)

At age 99, Dick Van Dyke avoids harmful foods, eats foods high in antioxidants, and keeps moving, a regimen that may have contributed to his astounding longevity.

Aging &amp; Longevity

The theory says our brain allocates resources to energy-consuming senescent cells at the body’s expense, accounting for gray hair, muscle shrinkage, and other signs of aging.

Model: C3B6F1 hybrid mice 
Dosage: 42 mg/kg of rapamycin and 1.44 mg/kg of trametinib in food starting at 6 months of age

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Researchers at the Max Planck Institute have unveiled that combining trametinib with rapamycin, drugs used in cancer treatment, extends average lifespan by 29% in female mice and 27% in male mice, respectively.

(The study’s lead author, Linda Partridge | The Biologist)

Combining two cancer treatment drugs, trametinib and rapamycin, extends lifespan by 29% and 27% in middle-aged female and male mice, respectively.

Model: Naturally aged C57BL/6J mice

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

A new study provides data suggesting compromised intestinal function with age and that fasting for short periods promotes intestinal regeneration and function in aged mice.

(A dysfunctional intestinal barrier that leaks harmful substances and bacteria into circulation develops with age | The Amino Company)

Alternate-day fasting, a form of intermittent fasting, reverses age-related intestinal barrier leakage in old mice.

Dr. Sinclair and collaborators show that an age-reversal technology that rejuvenates cells protects neurons from inflammation and cell death in mice. 

Search Result: Inflammaging

99-Year-Old Dick Van Dyke’s Secrets to Thriving Longevity

Are Senescent Cells Turning Your Hair Gray? A New Aging Theory

Latest Research: Two FDA-Approved Drugs Additively Extend Lifespan

Can Intermittent Fasting Slow Down Gut Aging? New Research Suggests So

Age-Reversal Tech Protects Against Neurodegeneration in Latest David Sinclair Study