Model: Male Monkeys 
Dosage: 20 mg/kg of metformin

Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys. 

Brain &amp; Neurons

Model: Adults with an average age of 61
Dosage: 1.2 grams of CoQ10 or 1.0 grams of NR administered orally daily for six weeks

What the New Kidney Disease Study Says About NR and CoQ10

Researchers conducted a human trial suggesting that nicotinamide riboside (NR) or CoQ10 supplementation improves metabolism and immunity.

(Three patients with chronic kidney disease undergoing a human trial | NAD.com)

NR or CoQ10 supplementation enhances gene activity associated with metabolism and immunity, CoQ10 reduces protein markers of inflammation, and NR improves mitochondrial function in patients with chronic kidney disease.

Scientists find that limiting folate (vitamin B9) beginning at mid-age leads to slowed aging in mice. 

Is reducing vitamin B9 intake good or bad in older age?

Aging &amp; Longevity

With over 246 million data points, obtained from 108 participants, scientists show that we rapidly age around 45 and 60. 

Stanford researchers find that our biological age accelerates during mid-life and retirement age. 

Dr. Mark Hyman’s Top Tips for an Effective Supplement Regimen in 2024

Dr. Mark Hyman recommends a multivitamin, fish oil, vitamin D, magnesium, probiotics, and creatine daily.

(Dr. Mark Hyman, an American physician who got six-pack abs in his 60s | Espotting)

Dr. Mark Hyman recommends six supplements to optimize longevity: a multivitamin, fish oil, vitamin D, magnesium, probiotics, and creatine.

Search Result: Heart Function

Metformin Slows Brain Aging in Older Monkeys, New Research Shows

What the New Kidney Disease Study Says About NR and CoQ10

How Not Eating Leafy Greens Can Make You Age Slower

Epic New Stanford Study Reveals Two Critical Phases of Rapid Aging in Our Lifetime

Dr. Mark Hyman’s Top Tips for an Effective Supplement Regimen in 2024