<p>Model: Ten-month-old male EFAD mice<br />
Dosage: 14.4 ppm of alfatradiol in diet for five months</p>


USC Study: Longevity-Promoting Drug Counteracts a Genetic Predisposition to Alzheimer's

The drug alfatradiol, also known as 17ɑ-estradiol, reduces cognitive errors on a test of memory and lowers neuronal plaques in mice genetically predisposed to Alzheimer’s disease.

(The University of Southern California | College Matchpoint)

Researchers unveil data suggesting the drug alfatradiol improves signs of frailty, reduces cognitive errors, and reduces neuronal plaques in mice with a genetic predisposition to Alzheimer’s disease.

Brain &amp; Neurons

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

Longevity Fanatic Bryan Johnson’s Daily Aging Intervention Routine for 2025

Aging guru Bryan Johnson shares his latest daily longevity protocol, which he uses to optimize measurements of his body’s aging.

(A futuristic image of Bryan Johnson | YouTube)

Venture capitalist and aging guru Bryan Johnson reveals his latest longevity-focused daily routine for 2025, focusing on sleep, exercise, and eating well.

Dr. Sinclair and collaborators show that an age-reversal technology that rejuvenates cells protects neurons from inflammation and cell death in mice. 

Lobster Leviathan God: Can Lobsters Live Forever?

An expired campaign to help a lobster continually molt raises the question of whether lobsters are immortal. 

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USC Study Suggests Longevity-Promoting Drug Counteracts a Genetic Predisposition to Alzheimer’s

Longevity Prescription

Longevity Fanatic Bryan Johnson’s Daily Aging Intervention Routine for 2025

Age-Reversal Tech Protects Against Neurodegeneration in Latest David Sinclair Study

Lobster Leviathan God: Can Lobsters Live Forever?