Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

University of Wisconsin researchers examine how reducing dietary protein intake may reshape nutrient sensing, metabolism, mitochondrial function, and other pathways linked to healthier aging.

(One of the leading authors on the Cell Press Blue article, Dr. Dudley Lamming | University of Wisconsin)

Researchers examine how restricting protein intake can improve metabolic health and influence aging-related pathways to extend healthspan and lifespan.

Aging &amp; Longevity

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

<p>Model: C57BL/6N mice<br />
Dosage: 1 g/kg carvedilol in food for one week followed by four weeks of PAGln treatment, consisting of 50 mg/kg per day by injection, and the same PAGln treatment for four weeks followed by 50 mg/kg per day of ABT263 via oral gavage for five days</p>


New Study Suggests Combining Senolytics with Blood Pressure Medication Counteracts an Aging Gut

Carvedilol, a blood pressure medication, and the senolytic agent ABT-263 both attenuate cellular senescence—an age-related, dysfunctional cellular state—driven by a gut bacterial metabolite in mice.

How to counteract age-related gut microbe alterations through diet, lifestyle interventions, and supplements. 

Counteracting the aging microbiome with a fiber-rich diet and supplements. 

Leading aging biology expert, Morgan Levine, Ph.D., says the scientific field of aging has a “major gender balance issue.”


Dr. Morgan Levine (image: Nicole Frappier/ The Guardian)

Morgan Levine triggers a flurry of responses on Twitter/X by saying there is gender imbalance in the field of aging biology. 

Search Result: Diversity

Protein Restriction and Longevity: Can Limiting Protein Intake Support Healthy Aging?

Longevity Prescription

Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study

How to Improve Gut Microbiome Health with Age

Female Longevity Scientist Points Out Gender Imbalance in Aging Field