A molecule known as miR-302b prolongs the life of mice by “waking up” senescent cells — “sleeping” cells that contribute to life-shortening chronic diseases. 

Depiction of microRNA molecules (Image: Artur Plawgo/iStock Photo/MIT.edu). 

Aging &amp; Longevity

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

The longevity biotech company, MetaShape, has a new compound designed to restore cellular nicotinamide adenine dinucleotide (NAD+) and offset elevated cholesterol, cognitive decline, and neurodegeneration.

<p>Model: 40 aged patients with COPD with an average age of 71.9<br />
Dosage: One gram of NR taken twice daily for a total of two grams per day for six weeks</p>


Fresh Insights: NR’s Effects on Inflammation in Age-Related Lung Disease

Taking nicotinamide riboside (NR) is tied to a 52.6% reduction of an inflammatory protein in the sputum—mucus coughed up from the respiratory tract—of patients with chronic obstructive pulmonary disease (COPD).

(Principal investigator Dr. Morten Scheibye-Knudsen, Associate Professor from the University of Copenhagen | Videnskab DK)

Bruce N. Ames, PhD, reveals his 11 longevity vitamins — molecules that activate long-term health enzymes — as part of his Triage Theory of aging. 

Triage Theory is named after the assortment system the French Army used during World War I called Triage, which prioritized the treatment of injured soldiers. 

 Peptide therapies, stem cell treatments, and NAD+ supplementation are being studied for their potential to thwart age-related decline. 

Search Result: DNA Repair

New Age-Reversal Therapy Prolongs Life by Targeting Senescent Cells

Biotech Startup Aims to Harness New NAD+-Related Drug Against Aging

Fresh Insights: NR’s Effects on Inflammation in Age-Related Lung Disease

Bruce Ames’ Triage Theory & The Eleven Longevity Vitamins

Can We Slow Down Aging? Inside the Cutting-Edge Science of Peptides, Stem Cells, and NAD+