NAD+ Supercharges Immune System Recovery in Older Mice

Researchers from the University of California, Berkeley, found that young mice need NAD+ breakdown, while old mice need NAD+ boosting.

Immunity

Longevity Expert Answers Aging Questions from X 

Levine answers questions about the latest aging biology research from social media posts. 


Morgan Levine, Ph.D. (image: USC Leonard Davis School of Gerontology). 

Longevity scientists Morgan Levine answers questions on aging from X. 

Aging &amp; Longevity

By 2024, SirTLab aims to begin human testing of therapies that activate SIRT6, an enzyme shown to extend the lifespan of mice. 


Depiction of SIRT6 enzyme bound to the senolytic quercetin (blue & red balls) and ADP-ribose (green & red balls) | Wikipedia

Industry

<p>Dose: 14 mg/kg rapamycin</p>
<p>Adminisration: mixed in chow (food)</p>


Rapamycin Extends Lifespan by Reorganizing DNA 

German and British scientists find that rapamycin, an inhibitor of mTOR, increases histone protein levels, leading to increased autophagy, improved gut health, and slightly increased lifespan in flies. 


Organs Can Age at Different Speeds

Chinese scientists utilize biological measurements from routine clinical checkups to determine the biological age of different organs in younger adults (20 to 45-years-old) that could aid in health management by predicting disease and mortality risk. 


Our organs run on separate "clocks," according to Shenzhen researchers, and these clocks can foretell death and disease.

Search Result: Centenarians

NAD+ Supercharges Immune System Recovery In Older Mice, Hurts Blood Stem Cells of Young Mice

Altos Labs’ Dr. Morgan Levine Answers the Internet’s Most Burning Questions on Aging

Biotech Startup SirTLab Prepares for Groundbreaking Human Trials of SIRT6-Boosting Therapy

Rapamycin Improves Longevity and Gut Health Through Rearrangement of DNA

Study Shows Organs Can Age at Different Speeds