Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes 

On 60 Minutes, Peter Attia reveals how performance, prevention, and emotional resilience contribute to aging well. 

Aging &amp; Longevity

Model: Male ApoE−/− mice fed a high-fat diet for 12 weeks to induce atherosclerosis.
Dosage: Methyl-β-cyclodextrin (Mß-CD) at 2.0 g/kg, subcutaneous injection, twice a week

 A new study shows cyclodextrin reduces artery plaques in mice by lowering cholesterol and blocking inflammatory cell death. 

Cardiovascular

Columbia University scientists find that inflammation increases the risk of common chronic age-related diseases only in people from industrialized populations. 

Columbia University in New York City (image: Columbia.edu). 

Immunity

Model: 24-month-old male C57BL/6J mice 
Dosage: 1% w/v of betaine for three weeks

The naturally occurring compound betaine is elevated in healthy adults after long-term exercise and mitigates signs of aging in mice. 

The interventions that may help fix or reset circadian rhythms, which decline with age. 

A representation of Kairos, not to be confused with Kronos (original image: misel-trogir.com).

Search Result: Cardiovascular Disease

Peter Attia’s 2025 Performance Principles for Longevity: 60 Minutes

Scientists Find a New Way to Stop Dangerous Artery Plaques From Growing

The Inflammation Myth: New Insights on Aging

“Exercise in a Pill”? Betaine Supplement Shows Anti-Aging Benefits

Beyond Aligning Life with Light: Supplements that Counter Circadian Decline