Model: 5xFAD mouse model for Alzheimer’s disease 
Dosage: Oral administration of 457 mg/kg/day of glucosamine for 2 weeks

Supplementing with glucosamine, a compound found in our cartilage, increases the risk of mortality from dementia in certain individuals while also worsening memory in mice that model dementia. 

Study led by Dr. Ramon Sun on the far right (image: mbi.ufl.edu). 

Brain &amp; Neurons

Discover proven anti-aging and longevity drugs that extend lifespan. Lifestyle, nutrition, sleep, exercise, and toxin avoidance, all in the best and most comprehensive guide.

Explore the most effective longevity interventions—nutrition, fasting, sleep, exercise, and mouse-tested drugs that extend lifespan in real studies.

Longevity Prescription: Diet, Fasting, and Proven Anti-Aging Strategies

Aging &amp; Longevity

Anti-aging enthusiast and multimillionaire Bryan Johnson warns against high uric acid levels and offers guidance on how to keep them low to slow aging. 

(Image: Bryan Johnson’s YouTube Channel) 

94-Year-Old Clint Eastwood’s Longevity Secrets

A series of realizations and personal experiences — like his father’s death from cardiovascular disease — have propelled Clint Eastwood to take care of his health for graceful aging.

Clint Eastwood has maintained his physical vigor into his 90s by eating lean meat and green, leafy vegetables, exercising in moderation, and maintaining an optimistic outlook.

100-Year-Old Nutrition Professor’s Lifestyle Tips for a Long Life

At 100, nutrition professor Dr. John Scharffenberg gives recommendations on how to prolong your life, such as exercising every day and eating a mostly vegetarian diet.

(Dr. John Scharffenberg with Plant Chompers host Michelle Cen | X)

Dr. John Scharffenberg, a 100-year-old nutrition professor at Loma Linda University, advises to cut out tobacco and alcohol use, exercise regularly, avoid meats and sugar, and limit saturated fat intake for a longer life.

Search Result: Avoiding alcohol

Common Joint Health Supplement May Progress Dementia, New Study Finds

Longevity Prescription

Bryan Johnson’s Free Guide to Slowing Aging

94-Year-Old Clint Eastwood’s Longevity Secrets

100-Year-Old Nutrition Professor’s Lifestyle Tips for a Long Life