Niacin (vitamin B3) triggers immune cells to attack human brain tumor initiating cells.

brain-tumor

Brain Tumor

Niacin, also called vitamin B3, stimulates immune cells to attack cells that initiate human brain tumors.

Combating Brain Cancer Using Common Vitamins

Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging

A combined treatment of NMN with 78c (a small molecule that inhibits an NAD+-degrading enzyme) enhances the effects of the anti-cancer CAR-T cell therapy in aged mice and human cells.

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CAR-T cancer

(A CAR-T cell [red] attacking a cancer cell [blue] | Crown Bioscience Blog)

Cancer

Popular physician Dr. Brad Stanfield says he takes finasteride to live longer, but is this a good idea?


monk

Monk

There is a debate over whether finasteride should be used to prevent prostate cancer, but some doctors are willing to take the potential risks. 

Rhonda Patrick Reveals How Intense Workouts Can Revolutionize Your Lifespan

Dr. Rhonda Patrick, a celebrity biochemist, discusses vigorous exercise’s remarkable potential to improve cognition and work against cancer.

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PATRICK

(Aging expert and celebrity biochemist Dr. Rhondra Patrick, PhD | podcastnotes.org)

Aging expert Dr. Rhonda Patrick explains how vigorous exercise improves cardiorespiratory fitness, enhances cognition, and works against cancer.

Aging &amp; Longevity

Model: C57/B6 female mice
Dosage: 300 mg/kg of ꞵ-hydroxybutyrate intraperitoneally injected three times per week for four weeks

Intermittent Fasting Potently Suppresses Tumor Growth: New Study Findings

Researchers show that intermittent fasting — going without food for 16-hour intervals per day — reduces tumor growth and extends lifespan in mice with ovarian cancer.

mousefood

MouseFood

(A mouse with an ovarian tumor next to a dish of food in a laboratory | NAD.com)

Intermittent fasting significantly extends remaining lifespan and suppresses tumor growth in mice with an aggressive and lethal form of ovarian cancer.

Model: NOD/SCID mice
Dosage: 3.4 mg/kg/day of neopetroside-B injected for three consecutive days

NAD+ Boosting Neopetroside-B Protects the Heart and Suppresses Cancer

Researchers show treatment with the nicotinamide adenine dinucleotide (NAD+) precursor neopetroside-B increases heart cell survival, prevents chemotherapy-induced heart scarring, and reduces tumor volume in mice.

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Neopetroside B (1)

(The molecular structure of the NAD+ precursor neopetroside-B)

Discover groundbreaking findings from a Korean study on Neopetroside-B's remarkable role in safeguarding the heart during chemotherapy while also exhibiting cancer-suppressing properties. Learn how NAD augmentation holds promise for enhanced cancer treatments.

NAD Boosting Neopetroside-B: Protecting the Heart during Chemotherapy & Suppressing Cancer – Korean Study

Vitamin D reduces human colorectal cancer cell growth by activating the NAD+ dependent enzyme sirtuin-1. 

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main

University of Rey Juan Carlos in Spain (photo: Eduardo Parra / Europa Press). 

Explore groundbreaking research from Spain revealing how Vitamin D activates NAD-dependent molecules to combat cancer. Discover the implications of this study and its potential in cancer treatment at NAD.com.

Vitamin D Activates NAD-Dependent Molecule to Combat Cancer: Research from Spain | NAD

Model: Human neuroblastoma (SK-N-BE(2)c), breast cancer (MDA-MB-468), and small-cell lung cancer (H82) cells; ES1e/SCID mice
Dosage: 500 nM of AOH1996 for 18 hours of cell treatment; 40 mg/kg of AOH1996 twice daily administered orally for mice

City of Hope Study Shows New Drug Kills Multiple Solid Tumors

Researchers demonstrate that an investigational small molecule selectively disrupts DNA repair and replication in cancer cells to suppress tumor growth in mice.

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MALKAS (1)

(The study’s principal investigator, Linda H. Malkas, PhD | Radiome.gr)

Discover the groundbreaking findings of the latest cancer study, unveiling a new chemotherapeutic agent's efficacy in targeting and killing various solid tumors. Explore the promising implications of this research at NAD.com.

Latest Cancer Study Reveals Breakthrough: New Chemotherapeutic Agent Targets Multiple Solid Tumors | NAD

Model: Male Wistar rats
Dosage: 1&#215;109 CFU of probiotics daily and 15 to 30 mg/kg of pterostilbene daily

Promising New Study: Probiotics Significantly Reduce Colon Cancer Risk

Probiotics reduce precancerous lesions and cancer-associated cellular proteins in the colon of carcinogen-exposed rats.

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CEARA (1)

(Federal University of Ceará | grancursosonline.com.br)

Supplementing with probiotics decreases the prevalence of tube-like glands called aberrant crypt foci in the colon that give rise to colorectal cancer, and adding pterostilbene increases antioxidant activity.

Model: Female BALB/c mouse model for colon cancer (C26-F)
Dosage (oral): 150 mg/kg/day of niacin

The NAD+ precursor niacin counters muscle mass and strength loss in a mouse model for colon cancer. 

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Corresponding scientist Dr. Eija Pirinen | University of Oulu 

Model: 18-month-old CD45.2 mice
Dosage: 4 ug Netrin-1 via injection; 5 injections total; once every 35 days

Researchers Rejuvenate Aged Mouse Blood Stem Cells

Infusing blood with a molecule critical for development, Netrin-1, improves the bone marrow niche in older people and restores the function of older blood stem cells, which has the potential to help people live longer.


Activating Immune Cells with a Common Vitamin to Fight Off Deadly Brain Cancer

Making CAR-T Cells Young Again: Restoring NAD+ to Rejuvenate Immunotherapy in Aging

Can Taking a Hair Growth Drug Delay Death from Cancer?

Rhonda Patrick Reveals How Intense Workouts Can Revolutionize Your Lifespan

Intermittent Fasting Potently Suppresses Tumor Growth to Prolong Survival: New Study Findings

NAD⁺ Boosting Molecule Protects the Heart Against Chemotherapy and Suppresses Cancer: Korean Study

Vitamin D Stops Cancer Growth by Activating NAD⁺ and Sirtuin-1: Research from Spain

City of Hope Study Shows New Drug Kills Multiple Solid Tumors

Promising New Study: Probiotics Significantly Reduce Colon Cancer Risk

Restoring NAD⁺ via Niacin Curtails Muscle Loss from Cancer: Italian & Finnish Scientists

Researchers Rejuvenate Aged Mouse Blood Stem Cells