Examining Evidence for the Cognition-Enhancing Potential of the Antioxidant Astaxanthin

The antioxidant astaxanthin significantly extends male mouse lifespan, and human research suggests it may help prevent age-related cognitive decline.

(An image of the red-orange pigment astaxanthin | Gruppo Farmalmpresa)

The potent antioxidant astaxanthin may have pro-longevity effects, and human trial data suggests it improves cognitive function in older adults.

Aging &amp; Longevity

Model: Older adults (60–85 years old) with mild cognitive impairment (MCI) enrolled in a randomized, double-blind, placebo-controlled clinical trial.
Dosage: Participants received one gastro-resistant capsule daily for 180 days, containing either 250 mg of Kluyveromyces fragilis yeast extract, 350 mg of Saccharomyces cerevisiae yeast extract, or a placebo.

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment

Daily supplementation with nucleotide-rich yeast extracts improves cognitive performance and mental well-being in older adults with mild cognitive impairment, researchers find. 

Brain &amp; Neurons

The NAD+ (nicotinamide adenine dinucleotide) precursor NR (nicotinamide riboside) counters sleep-deprivation-induced cognitive deficits in rats with excess Alzheimer’s plaques. 


Model: 8-month-old female Swiss mice
Dosage: 200 µL of aged-derived fecal suspension administered orally three days per week for two weeks

New Study: Transferring Gut Microbes from Old to Adult Mice Shortens Lifespan

Spanish scientists unveil data showing that transferring fecal microbes from old to adult mice increases biological age and shortens lifespan.

(A depiction of the intestines filled with gut microbes | Northwestern Medicine)

Spanish scientists show that transferring fecal microbes from old to adult mice increases biological age and shortens lifespan.

Joe Rogan’s Top Supplements for 2026

Joe Rogan’s latest supplement stack includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

(Joe Rogan on set for his podcast | Spotify Newsroom)

Joe Rogan’s updated supplement stack for 2026 includes compounds targeting longevity, cognition, immunity, fitness, and optimal hormone levels.

Search Result: Oxidative Stress

Examining Evidence for the Cognition-Enhancing Potential of the Antioxidant Astaxanthin

Yeast Supplement Improves Cognitive Function in Older Adults with Mild Cognitive Impairment

NAD+ Booster Counters Cognitive Deficits of Sleep Deprivation, New Study Shows

New Study: Transferring Gut Microbes from Old to Adult Mice Shortens Lifespan

Joe Rogan’s Top Supplements for 2026