<p>Model: Male Monkeys </p>
<p>Dosage: 20 mg/kg/day of metformin </p>


Supplementation of metformin — a first-line treatment for type 2 diabetes and the second-most prescribed medication in the U.S. — improves the learning and memory of older monkeys. 

Brain &amp; Neurons

Four FDA-Approved Drugs that Reduce Chances of Aging-Related Death

Dr. Nir Barzilai, the director of aging research at Albert Einstein College of Medicine, discusses the science behind SGLT2 inhibitors, metformin, bisphosphonates, and GLP-1 agonists.

Dr. Nir Barzilai, the director of aging research at Albert Einstein College of Medicine, relays that we have four FDA-approved drugs that lower human mortality: SGLT2 inhibitors, bisphosphonates, metformin, and GLP-1 agonists.

Aging &amp; Longevity

Bezos and Zuckerberg Invest Millions to Live Longer While Musk Refuses

Amazon founder Jeff Bezos is investing in the aging research company Unity Biotechnology, while Facebook pioneer Mark Zuckerberg annually awards $3 million to aging scientists, yet Elon Musk caustically criticizes these endeavors.

(The world’s wealthiest man and founder of SpaceX, Elon Musk | SFGate)

Billionaires Jeff Bezos and Mark Zuckerberg are investing full-force into anti-aging research; however, Elon Musk rebukes these contributions, saying extending lifespan will cause society to stagnate.

By 2024, SirTLab aims to begin human testing of therapies that activate SIRT6, an enzyme shown to extend the lifespan of mice. 


Depiction of SIRT6 enzyme bound to the senolytic quercetin (blue & red balls) and ADP-ribose (green & red balls) | Wikipedia

Search Result: Nir Barzilai

Metformin Slows Brain Aging in Older Monkeys, New Research Shows

Four FDA-Approved Drugs that Reduce Chances of Aging-Related Death

Bezos and Zuckerberg Invest Millions to Live Longer While Musk Refuses

Biotech Startup SirTLab Prepares for Groundbreaking Human Trials of SIRT6-Boosting Therapy