Aside from diet and exercise, senolytics — compounds that remove age-promoting cells — may rejuvenate the immune system and reduce the risk of neurodegeneration and dementia. 

Brain &amp; Neurons

Model: 3-month-old LDLR−/− pigs
Dosage: 400 nM of SWNT or SWNT-SHP1i 
was infused intravenously for ~15–30 min, once a week, for 12 weeks

“Trojan Horse” Nanoparticles: A Breakthrough in Treatment for Atherosclerosis 

Stanford School of Medicine researchers develop safe nanoparticles that target dying cells in atherosclerotic plaque and reduce vascular inflammation.

Cardiovascular

New Study Shows How Boosting NAD+ Could Protect Against Parkinson’s

Recent research from Zhejiang University School of Medicine in Hangzhou, China, demonstrates that administering NAD+ precursors to mice can safeguard the brain against neurodegeneration

(Zhejiang University School of Medicine | Panda Admission)

Model: Male Wistar rats (4-month-old young rats and 24-month-old old rats)
Dosage: Oral administration of the trypsin inhibitor tranexamic acid in drinking water for 14 days at a minimum dose of 0.39 g/kg/day after consuming about 40 mL/day of water

Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within

University of California, San Diego researchers show digestive enzyme leakage from the intestines contributes to organ damage in old rats, offering what may be a new way to explain aging.

(Principal investigator, Geert Schmid-Schönbein | voiceofsandiego.org)

Aging &amp; Longevity

Stem cell therapy improves the reproductive potential of monkeys, with one aged monkey becoming pregnant.

(Image: labroots.com) Cynomolgus monkeys. 

Search Result: Inflammation

Israeli Scientists Proclaim ‘A Healthy Mind Is a Healthy Immune System,’ Revealing How to Slow Brain Aging

“Trojan Horse” Nanoparticles: A Breakthrough in Treatment for Atherosclerosis

New Study Shows How Boosting NAD+ Could Protect Against Parkinson’s

Newly Proposed Aging Mechanism: Digestive Enzymes May Be Eating Us from Within

Stem Cells Prolong Reproductive Lifespan, New Study Shows