Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

A new human study shows that a procedure involving the replacement of blood plasma with a fresh solution (therapeutic plasma exchange) lowers a measure of how quickly the body is aging (biological age).

(The Buck Institute for Research on Aging | Facebook)

In a first-of-its-kind human trial, participants who underwent therapeutic plasma exchange exhibited significantly lowered biological age.

Aging &amp; Longevity

Exploring Longevity Drugs in an Era of Slumping Investments and Rising Doubt

Venture capitalists have put the brakes on investments in longevity-related interventions over the past few years, yet experts predict new drug approvals will spur a funding surge.

Despite slumping investments in longevity-related biotech companies over the last few years, experts predict a funding surge as new therapies get closer to approval.

Industry

<p>Model: 18-month-old C57BL/6J mice </p>
<p>Dose (oral): 5 mg/kg of dasatinib combined with 50 mg/kg of quercetin</p>


Senolytics Restore Age-Related Heart-Brain Connection Loss

Treating old mice with two senolytics — compounds that remove senescent (dysfunctional) cells —  called dasatinib and quercetin prevents heart-brain connection loss and irregular heart rhythms.  


Principal Investigator Dr. Stefanie Dimmeler | DZHK 

Cardiovascular

The Most Important Anti-Aging Drugs and Interventions

President and CEO of the Buck Institute for Research on Aging Eric Verdin, M.D., discusses the future of anti-aging drugs and the most important interventions to improve lifespan. 

An immune system enzyme called CD38 is associated with low NAD+ levels, shortened reproductive lifespan, and fertility problems in female mice.  


Search Result: Eric Verdin

Latest Human Trial from the Buck Institute Shows Plasma Exchange Lowers Biological Age

Exploring Longevity Drugs in an Era of Slumping Investments and Rising Doubt

German Study Shows Senolytics Restore Heart-Brain Connection to Reverse Cardiac Aging

Longevity Expert Dr. Eric Verdin: The Most Important Anti-Aging Drugs and Interventions

Buck Institute Study Shows Low NAD+ Drives Reproductive Aging and Hinders Fertility