<p>Model: Young C57BL/6J mice fed a high protein (56% of daily calories) diet for 20 weeks </p>
<p>Dosage: Injection with either 400 mg/kg of NMN or 20 mg/kg of 78c for 4 weeks</p>


High protein intake improves the body composition of aged mice, but it lowers NAD+ (nicotinamide adenine dinucleotide) levels and promotes metabolic aging. 

Metabolism

How to Boost Mitochondrial Density and Quality for Longevity

Lifestyle hacks contrived to promote the tissue density and quality of mitochondria (the cell’s powerhouses) can aid in the efficient generation of cellular energy and reduce inflammation, thereby promoting longevity.

(A colorized image of mitochondria taken with a transmission electron microscope | UC San Diego Today)

Exercise, nutritional support, and lifestyle hacks like cold exposure can all help mitigate mitochondrial dysfunction, a key hallmark of aging.

Aging &amp; Longevity

NAD+ (nicotinamide adenine dinucleotide) may contribute to healthy cellular aging by enhancing biological energy flow, according to the newly formulated energy resistance principle.


The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

According to French scientists, no organ system appears as vulnerable to aging as the cardiovascular system, and anti-aging therapeutics may help mitigate the effects of cardiovascular disease.

(The principal investigator behind the review, aging researcher Guido Kroemer | Olympiad in Cardiovascular Medicine)

Anti-aging therapeutics may prevent and slow age-related cardiovascular dysfunction.

Cardiovascular

The theory says our brain allocates resources to energy-consuming senescent cells at the body’s expense, accounting for gray hair, muscle shrinkage, and other signs of aging.

Search Result: Calorie Restriction

High Protein Intake Promotes Aging by Lowering NAD+ Levels

How to Boost Mitochondrial Density and Quality for Longevity

Boosting NAD+ May Defy Aging by Enhancing Energy Flow, According to a New Theory

The Latest Insight on Anti-Aging Therapeutics Targeting Cardiovascular Disease

Are Senescent Cells Turning Your Hair Gray? A New Aging Theory