Leading aging biology expert, Morgan Levine, Ph.D., says the scientific field of aging has a “major gender balance issue.”


Dr. Morgan Levine (image: Nicole Frappier/ The Guardian)

Morgan Levine triggers a flurry of responses on Twitter/X by saying there is gender imbalance in the field of aging biology. 

Others

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest "Longevity Drug" Seragon RESTORIN Make the List 

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon RESTORIN. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Explore the top 10 new drugs of 2023, featuring breakthroughs like weight-loss wonder Tirzpatide and longevity drug Seragon Restorin. Dive into advancements targeting aging, rare diseases, and conditions like Alzheimer's Disease.

Aging &amp; Longevity

Manipulating Aging Through Cutting-Edge Gene Therapies

Gene therapy techniques like CRISPR and RNA replacement compensate for or replace defective longevity-associated genes like KLOTHO or FOXO genes.

(A scientist in a laboratory performing gene therapy research)

Researchers continue to develop ways to substitute, edit, and delete gene sequences to engineer and improve the expression of certain genes related to aging.

Reviews

Model: NAD+-deficient mice
Dosage (oral): 400 mg/kg of nicotinamide riboside (NR)

Chinese scientists enhance the fertility of middle-aged mice with nicotinamide riboside (NR) by addressing the cellular metabolic deficits associated with aging ovaries.

4-cell embryos from the ovaries of mice given NR. 

 Explore the findings of a new study revealing the potential of NR (nicotinamide riboside) in enhancing female reproductive lifespan and promoting fertility in middle age. Discover the impact of NAD (nicotinamide adenine dinucleotide) supplementation on reproductive health and the promising advancements in fertility research. Read more on NAD.

New Study Shows NR Enhances Female Reproductive Lifespan and Promotes Fertility in Middle Age - NAD

Metabolism

Model: C57BL/6J mice
Dosage: 1 mg/mL for a total of 3 mL daily of abacavir dissolved in drinking water for six months

Latest Report: Ancient Virus Reawakens in Older Ages to Accelerate Aging

Latent viral sequences in DNA have evolved with mutations to render them inactive, yet the most recently inherited of these lack suppression, and their activity drives aging.

(Transmission electron microscopy images of young human cells treated with medium from young cells [top] and senescent cells [bottom]. The cell on the bottom treated with senescent cell medium exhibits a dark circle that is a retrovirus-like protein.)

Viral sequences inserted into DNA during ancient viral infections can become activated as we get older, driving cellular senescence and aging.

Search Result: CRISPR

Female Longevity Scientist Points Out Gender Imbalance in Aging Field

2023 Top 10 New Drugs: Weight-loss Wonder Drug Tirzpatide, Strongest “Longevity Elixir” Seragon RESTORIN Make the List

Manipulating Aging through Cutting-Edge Gene Therapies

New Study Shows NR Enhances Female Reproductive Lifespan and Promotes Fertility in Middle-Age

Latest Report: Ancient Virus Reawakens in Older Ages to Accelerate Aging