Model: Ten-month-old male EFAD mice 
Dosage: 14.4 ppm of alfatradiol in diet for five months

USC Study: Longevity-Promoting Drug Counteracts a Genetic Predisposition to Alzheimer's

The drug alfatradiol, also known as 17ɑ-estradiol, reduces cognitive errors on a test of memory and lowers neuronal plaques in mice genetically predisposed to Alzheimer’s disease.

(The University of Southern California | College Matchpoint)

Researchers unveil data suggesting the drug alfatradiol improves signs of frailty, reduces cognitive errors, and reduces neuronal plaques in mice with a genetic predisposition to Alzheimer’s disease.

Brain &amp; Neurons

A 167-study analysis reveals that rapamycin prolongs lifespan as effectively as dietary restriction: reducing food intake without entering a state of malnourishment.

Aging &amp; Longevity

The UN’s Brief on the Biology of Aging

A new brief from the United Nations (UN) Scientific Advisory Board examines the latest developments in geroscience—a field devoted to delaying, preventing, and treating diseases linked to aging.

A new United Nations brief examines how researchers are addressing an aging global population with geroscience—a field seeking to understand how to intervene against aging.

Model: 27-month-old male C57BL/6N mice 
Dosage: 50 mg/kg/day of fisetin for 1 week, followed by no treatment for 2 weeks, followed by another week of treatment

Plant-based molecule fisetin preserves muscle mass and strength in older mice via senolytic action — removal of senescent (dysfunctional) cells.


Study conducted at the University of Colorado Boulder (image: govtech.com) 

Skin &amp; Muscle

A drug discovered and designed by artificial intelligence (AI) improves the breathing capacity of individuals with age-related lung disease. 


Alex Zhavoronkov, PhD, founder and CEO of Insilco Medicine, a biotechnology company that recently deployed the humanoid robot he stands beside (image: insilico.com). 

Search Result: CAR T

USC Study Suggests Longevity-Promoting Drug Counteracts a Genetic Predisposition to Alzheimer’s

Anti-Aging Drug Rapamycin Extends Life as Much as Dieting, New Study Shows

The UN’s Brief on the Biology of Aging

Fisetin Fights Frailty: New Study Shows Supplment Preserves Strength

AI-Made Drug Reverses Lung Aging: First Human Trial Results