<p>Model: C57BL/6N mice<br />
Dosage: 1 g/kg carvedilol in food for one week followed by four weeks of PAGln treatment, consisting of 50 mg/kg per day by injection, and the same PAGln treatment for four weeks followed by 50 mg/kg per day of ABT263 via oral gavage for five days</p>


New Study Suggests Combining Senolytics with Blood Pressure Medication Counteracts an Aging Gut

Carvedilol, a blood pressure medication, and the senolytic agent ABT-263 both attenuate cellular senescence—an age-related, dysfunctional cellular state—driven by a gut bacterial metabolite in mice.

Aging &amp; Longevity

Ezra launches a $5,995 longevity scan with Bryan Johnson, using advanced imaging to detect early signs of aging, cancer, and key health risks.









Abdominal fat is associated with a dramatic increase in the risk of early death in generally healthy older adults who are not obese. 

(Image: AARP / AHMET YARALI / GETTY IMAGES)

Metabolism

Clinical trials show that urolithin A enhances muscle strength and reduces inflammation. 

Skin &amp; Muscle

Is the Viral Anti-Aging Diet-In-a-Box Worth It?

A $200, five-day fasting-mimicking diet in a box is claiming to “fuel your body into rejuvenation, longevity, and healthy living.”

(The ProLon fasting-mimicking diet package | Habitually Chic)

A fasting-mimicking diet that costs $200 claims to fuel your body into rejuvenation, longevity, and healthy living.

Search Result: Body composition

Combining Senolytics with Blood Pressure Medication Counteracts Gut Aging and Promotes Longevity, Suggests New Study

Would You Pay $6,000 to Know What Might Kill You?

New Research Study Claims Belly Fat Increases Risk of Early Death by Whopping 365%

Urolithin A Side Effects, Benefits, and Dosage

Is the Viral Anti-Aging Diet-In-a-Box Worth It?