Model: Male C57BL/6J (B6) mice (15 months old at the start of treatment)
Dosage: Approximately 5 mg/kg/day of S-1-propenyl-L-cysteine (S1PC) was administered orally for 8 months, from 15 to 23 months of age. S1PC was given in chow containing 0.0025% S1PC, with a second experiment using drinking water to confirm the findings.

Researchers found that a compound found in garlic supports healthier muscle aging by boosting cellular defenses linked to longevity and maintaining physical performance.

Skin &amp; Muscle

Model: SAMP8 mice (5 months old) and C57BL/6 mice (16 months old)
Dosage: 1.5 mg/kg of urolithin A was administered by intraperitoneal injection three times per week (Monday, Wednesday, and Friday) for 8 weeks.

Study shows that urolithin A preserves memory and cognitive function during aging when treatment begins before age-related decline, but does not reverse cognitive impairment once it is established.

Brain &amp; Neurons

Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The XPrize Healthspan—which will split $101 million among teams developing therapeutics to restore muscle, cognitive, and immune function in older adults—has named 10 teams receiving $1 million each.

(XPrize announced the finalists for its XPrize Healthspan competition | XPrize)

The XPrize Healthspan competition has named its top 20 finalist groups that will submit their aging intervention therapies for human trial testing.

Aging &amp; Longevity

The Overlooked Organ That Could Hold the Key to Fighting Aging

Scientists are researching ways to regrow the thymus, an immune organ that vanishes with age, to suppress the tolls of aging.

(The thymus [colored orange] is located in the upper chest | NAD.com)

An organ involved in immunity, the thymus, vanishes as people get older, and scientists are researching ways to regrow it to fight aging.

Immunity

Model: Male Wistar rats 
Dosage: 1.5 g/kg/day of orally administered glycine for 5 months

Glycine, an amino acid shown to extend the lifespan of mice, moderately extends the lifespan of flies and counters brain and muscle degeneration in aged rats. 

Search Result: Brain metabolism

Garlic-Derived Compound Activates a Natural Anti-Aging Pathway That Preserves Muscle Function

Urolithin A Preserves Memory During Aging When Treatment Begins Early, Study Shows

10 Finalist Teams Awarded $1 Million in XPrize Healthspan Contest to Transform Healthy Aging

The Overlooked Organ That Could Hold the Key to Fighting Aging

Glycine Extends Life & Counters Brain and Muscle Degeneration, New Study Shows